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Electrophilic fatty acid species inhibit 5-lipoxygenase and attenuate sepsis-induced pulmonary inflammation.
Awwad K, Steinbrink SD, Frömel T, Lill N, Isaak J, Häfner AK, Roos J, Hofmann B, Heide H, Geisslinger G, Steinhilber D, Freeman BA, Maier TJ, Fleming I. Awwad K, et al. Among authors: fleming i. Antioxid Redox Signal. 2014 Jun 10;20(17):2667-80. doi: 10.1089/ars.2013.5473. Epub 2014 Feb 3. Antioxid Redox Signal. 2014. PMID: 24206143 Free PMC article.
Inhibition of the soluble epoxide hydrolase by tyrosine nitration.
Barbosa-Sicard E, Frömel T, Keserü B, Brandes RP, Morisseau C, Hammock BD, Braun T, Krüger M, Fleming I. Barbosa-Sicard E, et al. Among authors: fleming i. J Biol Chem. 2009 Oct 9;284(41):28156-28163. doi: 10.1074/jbc.M109.054759. Epub 2009 Aug 24. J Biol Chem. 2009. PMID: 19704161 Free PMC article.
Soluble epoxide hydrolase deficiency attenuates neointima formation in the femoral cuff model of hyperlipidemic mice.
Revermann M, Schloss M, Barbosa-Sicard E, Mieth A, Liebner S, Morisseau C, Geisslinger G, Schermuly RT, Fleming I, Hammock BD, Brandes RP. Revermann M, et al. Among authors: fleming i. Arterioscler Thromb Vasc Biol. 2010 May;30(5):909-14. doi: 10.1161/ATVBAHA.110.204099. Epub 2010 Mar 11. Arterioscler Thromb Vasc Biol. 2010. PMID: 20224052 Free PMC article.
Molecular pharmacological profile of a novel thiazolinone-based direct and selective 5-lipoxygenase inhibitor.
Hofmann B, Rödl CB, Kahnt AS, Maier TJ, Michel AA, Hoffmann M, Rau O, Awwad K, Pellowska M, Wurglics M, Wacker M, Zivković A, Fleming I, Schubert-Zsilavecz M, Stark H, Schneider G, Steinhilber D. Hofmann B, et al. Among authors: fleming i. Br J Pharmacol. 2012 Apr;165(7):2304-13. doi: 10.1111/j.1476-5381.2011.01707.x. Br J Pharmacol. 2012. PMID: 21955369 Free PMC article.
620 results