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Quantitative analysis of target coverage and germinal center response by a CXCL13 neutralizing antibody in a T-dependent mouse immunization model.
Brodfuehrer J, Rankin A, Edmonds J, Keegan S, Andreyeva T, Lawrence-Henderson R, Ozer J, Gao H, Bloom L, Boisvert A, Lam K, Lee J, LaBranche T, Syed J, Miao W, Singh P. Brodfuehrer J, et al. Among authors: labranche t. Pharm Res. 2014 Mar;31(3):635-48. doi: 10.1007/s11095-013-1185-2. Epub 2013 Nov 5. Pharm Res. 2014. PMID: 24190631
JAK inhibition with tofacitinib suppresses arthritic joint structural damage through decreased RANKL production.
LaBranche TP, Jesson MI, Radi ZA, Storer CE, Guzova JA, Bonar SL, Thompson JM, Happa FA, Stewart ZS, Zhan Y, Bollinger CS, Bansal PN, Wellen JW, Wilkie DP, Bailey SA, Symanowicz PT, Hegen M, Head RD, Kishore N, Mbalaviele G, Meyer DM. LaBranche TP, et al. Arthritis Rheum. 2012 Nov;64(11):3531-42. doi: 10.1002/art.34649. Arthritis Rheum. 2012. PMID: 22899318 Free article.
Modulation of innate and adaptive immune responses by tofacitinib (CP-690,550).
Ghoreschi K, Jesson MI, Li X, Lee JL, Ghosh S, Alsup JW, Warner JD, Tanaka M, Steward-Tharp SM, Gadina M, Thomas CJ, Minnerly JC, Storer CE, LaBranche TP, Radi ZA, Dowty ME, Head RD, Meyer DM, Kishore N, O'Shea JJ. Ghoreschi K, et al. J Immunol. 2011 Apr 1;186(7):4234-43. doi: 10.4049/jimmunol.1003668. Epub 2011 Mar 7. J Immunol. 2011. PMID: 21383241 Free PMC article.
Zucker Lean Rats With Hepatic Steatosis Recapitulate Asymptomatic Metabolic Syndrome and Exhibit Greater Sensitivity to Drug-Induced Liver Injury Compared With Standard Nonclinical Sprague-Dawley Rat Model.
LaBranche TP, Kopec AK, Mantena SR, Hollingshead BD, Harrington AW, Stewart ZS, Zhan Y, Hayes KD, Whiteley LO, Burdick AD, Davis JW 2nd. LaBranche TP, et al. Toxicol Pathol. 2020 Dec;48(8):994-1007. doi: 10.1177/0192623320968716. Epub 2020 Nov 28. Toxicol Pathol. 2020. PMID: 33252024
25 results