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Inhibition of mitochondrial pyruvate transport by zaprinast causes massive accumulation of aspartate at the expense of glutamate in the retina.
Du J, Cleghorn WM, Contreras L, Lindsay K, Rountree AM, Chertov AO, Turner SJ, Sahaboglu A, Linton J, Sadilek M, Satrústegui J, Sweet IR, Paquet-Durand F, Hurley JB. Du J, et al. Among authors: sadilek m. J Biol Chem. 2013 Dec 13;288(50):36129-40. doi: 10.1074/jbc.M113.507285. Epub 2013 Nov 1. J Biol Chem. 2013. PMID: 24187136 Free PMC article.
Interfacial enzymology of parvovirus phospholipases A2.
Canaan S, Zádori Z, Ghomashchi F, Bollinger J, Sadilek M, Moreau ME, Tijssen P, Gelb MH. Canaan S, et al. Among authors: sadilek m. J Biol Chem. 2004 Apr 9;279(15):14502-8. doi: 10.1074/jbc.M312630200. Epub 2004 Jan 15. J Biol Chem. 2004. PMID: 14726513 Free article.
Roles of glucose in photoreceptor survival.
Chertov AO, Holzhausen L, Kuok IT, Couron D, Parker E, Linton JD, Sadilek M, Sweet IR, Hurley JB. Chertov AO, et al. Among authors: sadilek m. J Biol Chem. 2011 Oct 7;286(40):34700-11. doi: 10.1074/jbc.M111.279752. Epub 2011 Aug 12. J Biol Chem. 2011. PMID: 21840997 Free PMC article.
Cytosolic reducing power preserves glutamate in retina.
Du J, Cleghorn W, Contreras L, Linton JD, Chan GC, Chertov AO, Saheki T, Govindaraju V, Sadilek M, Satrústegui J, Hurley JB. Du J, et al. Among authors: sadilek m. Proc Natl Acad Sci U S A. 2013 Nov 12;110(46):18501-6. doi: 10.1073/pnas.1311193110. Epub 2013 Oct 14. Proc Natl Acad Sci U S A. 2013. PMID: 24127593 Free PMC article.
Phototransduction Influences Metabolic Flux and Nucleotide Metabolism in Mouse Retina.
Du J, Rountree A, Cleghorn WM, Contreras L, Lindsay KJ, Sadilek M, Gu H, Djukovic D, Raftery D, Satrústegui J, Kanow M, Chan L, Tsang SH, Sweet IR, Hurley JB. Du J, et al. Among authors: sadilek m. J Biol Chem. 2016 Feb 26;291(9):4698-710. doi: 10.1074/jbc.M115.698985. Epub 2015 Dec 16. J Biol Chem. 2016. PMID: 26677218 Free PMC article.
Reductive carboxylation is a major metabolic pathway in the retinal pigment epithelium.
Du J, Yanagida A, Knight K, Engel AL, Vo AH, Jankowski C, Sadilek M, Tran VT, Manson MA, Ramakrishnan A, Hurley JB, Chao JR. Du J, et al. Among authors: sadilek m. Proc Natl Acad Sci U S A. 2016 Dec 20;113(51):14710-14715. doi: 10.1073/pnas.1604572113. Epub 2016 Dec 1. Proc Natl Acad Sci U S A. 2016. PMID: 27911769 Free PMC article.
Biochemical adaptations of the retina and retinal pigment epithelium support a metabolic ecosystem in the vertebrate eye.
Kanow MA, Giarmarco MM, Jankowski CS, Tsantilas K, Engel AL, Du J, Linton JD, Farnsworth CC, Sloat SR, Rountree A, Sweet IR, Lindsay KJ, Parker ED, Brockerhoff SE, Sadilek M, Chao JR, Hurley JB. Kanow MA, et al. Among authors: sadilek m. Elife. 2017 Sep 13;6:e28899. doi: 10.7554/eLife.28899. Elife. 2017. PMID: 28901286 Free PMC article.
An Analysis of Metabolic Changes in the Retina and Retinal Pigment Epithelium of Aging Mice.
Tsantilas KA, Cleghorn WM, Bisbach CM, Whitson JA, Hass DT, Robbings BM, Sadilek M, Linton JD, Rountree AM, Valencia AP, Sweetwyne MT, Campbell MD, Zhang H, Jankowski CSR, Sweet IR, Marcinek DJ, Rabinovitch PS, Hurley JB. Tsantilas KA, et al. Among authors: sadilek m. Invest Ophthalmol Vis Sci. 2021 Nov 1;62(14):20. doi: 10.1167/iovs.62.14.20. Invest Ophthalmol Vis Sci. 2021. PMID: 34797906 Free PMC article.
84 results