Belfort GM - Search Results

1

The major brain cholesterol metabolite 24(S)-hydroxycholesterol is a potent allosteric modulator of N-methyl-D-aspartate receptors.

Paul SM, Doherty JJ, Robichaud AJ, Belfort GM, Chow BY, Hammond RS, Crawford DC, Linsenbardt AJ, Shu HJ, Izumi Y, Mennerick SJ, Zorumski CF. Paul SM, et al. Among authors: belfort gm. J Neurosci. 2013 Oct 30;33(44):17290-300. doi: 10.1523/JNEUROSCI.2619-13.2013. J Neurosci. 2013. PMID: 24174662 Free PMC article.

2

Neuroactive Steroids. 2. 3α-Hydroxy-3β-methyl-21-(4-cyano-1H-pyrazol-1'-yl)-19-nor-5β-pregnan-20-one (SAGE-217): A Clinical Next Generation Neuroactive Steroid Positive Allosteric Modulator of the (γ-Aminobutyric Acid)_A Receptor.

Martinez Botella G, Salituro FG, Harrison BL, Beresis RT, Bai Z, Blanco MJ, Belfort GM, Dai J, Loya CM, Ackley MA, Althaus AL, Grossman SJ, Hoffmann E, Doherty JJ, Robichaud AJ. Martinez Botella G, et al. Among authors: belfort gm. J Med Chem. 2017 Sep 28;60(18):7810-7819. doi: 10.1021/acs.jmedchem.7b00846. Epub 2017 Aug 17. J Med Chem. 2017. PMID: 28753313

3

Preclinical characterization of zuranolone (SAGE-217), a selective neuroactive steroid GABA_A receptor positive allosteric modulator.

Althaus AL, Ackley MA, Belfort GM, Gee SM, Dai J, Nguyen DP, Kazdoba TM, Modgil A, Davies PA, Moss SJ, Salituro FG, Hoffmann E, Hammond RS, Robichaud AJ, Quirk MC, Doherty JJ. Althaus AL, et al. Among authors: belfort gm. Neuropharmacology. 2020 Dec 15;181:108333. doi: 10.1016/j.neuropharm.2020.108333. Epub 2020 Sep 22. Neuropharmacology. 2020. PMID: 32976892 Free PMC article.

4

A new method for determining levels of sedation in dogs: A pilot study with propofol and a novel neuroactive steroid anesthetic.

Youngblood BL, Ueyama Y, Muir WW, Belfort GM, Hammond RH, Dai J, Salituro FG, Robichaud AJ, Doherty JJ. Youngblood BL, et al. Among authors: belfort gm. J Neurosci Methods. 2018 Jul 15;305:82-88. doi: 10.1016/j.jneumeth.2018.05.006. Epub 2018 May 23. J Neurosci Methods. 2018. PMID: 29772269

5

Neuroactive Steroids. 1. Positive Allosteric Modulators of the (γ-Aminobutyric Acid)A Receptor: Structure-Activity Relationships of Heterocyclic Substitution at C-21.

Martinez Botella G, Salituro FG, Harrison BL, Beresis RT, Bai Z, Shen K, Belfort GM, Loya CM, Ackley MA, Grossman SJ, Hoffmann E, Jia S, Wang J, Doherty JJ, Robichaud AJ. Martinez Botella G, et al. Among authors: belfort gm. J Med Chem. 2015 Apr 23;58(8):3500-11. doi: 10.1021/acs.jmedchem.5b00032. Epub 2015 Apr 14. J Med Chem. 2015. PMID: 25799373

6

High-performance genetically targetable optical neural silencing by light-driven proton pumps.

Chow BY, Han X, Dobry AS, Qian X, Chuong AS, Li M, Henninger MA, Belfort GM, Lin Y, Monahan PE, Boyden ES. Chow BY, et al. Among authors: belfort gm. Nature. 2010 Jan 7;463(7277):98-102. doi: 10.1038/nature08652. Nature. 2010. PMID: 20054397 Free PMC article.

7

Cerebellar neurons possess a vesicular compartment structurally and functionally similar to Glut4-storage vesicles from peripheral insulin-sensitive tissues.

Bakirtzi K, Belfort G, Lopez-Coviella I, Kuruppu D, Cao L, Abel ED, Brownell AL, Kandror KV. Bakirtzi K, et al. J Neurosci. 2009 Apr 22;29(16):5193-201. doi: 10.1523/JNEUROSCI.0858-09.2009. J Neurosci. 2009. PMID: 19386915 Free PMC article.

8

Npas4 regulates a transcriptional program in CA3 required for contextual memory formation.

Ramamoorthi K, Fropf R, Belfort GM, Fitzmaurice HL, McKinney RM, Neve RL, Otto T, Lin Y. Ramamoorthi K, et al. Among authors: belfort gm. Science. 2011 Dec 23;334(6063):1669-75. doi: 10.1126/science.1208049. Science. 2011. PMID: 22194569 Free PMC article.

9

Cellugyrin and synaptogyrin facilitate targeting of synaptophysin to a ubiquitous synaptic vesicle-sized compartment in PC12 cells.

Belfort GM, Kandror KV. Belfort GM, et al. J Biol Chem. 2003 Nov 28;278(48):47971-8. doi: 10.1074/jbc.M304174200. Epub 2003 Aug 18. J Biol Chem. 2003. PMID: 12928441 Free article.

10

Cellugyrin induces biogenesis of synaptic-like microvesicles in PC12 cells.

Belfort GM, Bakirtzi K, Kandror KV. Belfort GM, et al. J Biol Chem. 2005 Feb 25;280(8):7262-72. doi: 10.1074/jbc.M404851200. Epub 2004 Dec 7. J Biol Chem. 2005. PMID: 15590695 Free article.

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