Chen T - Search Results

1

A DNMT3A mutation common in AML exhibits dominant-negative effects in murine ES cells.

Kim SJ, Zhao H, Hardikar S, Singh AK, Goodell MA, Chen T. Kim SJ, et al. Among authors: chen t. Blood. 2013 Dec 12;122(25):4086-9. doi: 10.1182/blood-2013-02-483487. Epub 2013 Oct 28. Blood. 2013. PMID: 24167195 Free PMC article.

2

A hypomorphic lsd1 allele results in heart development defects in mice.

Nicholson TB, Singh AK, Su H, Hevi S, Wang J, Bajko J, Li M, Valdez R, Goetschkes M, Capodieci P, Loureiro J, Cheng X, Li E, Kinzel B, Labow M, Chen T. Nicholson TB, et al. Among authors: chen t. PLoS One. 2013 Apr 24;8(4):e60913. doi: 10.1371/journal.pone.0060913. Print 2013. PLoS One. 2013. PMID: 23637775 Free PMC article.

3

Tet family of 5-methylcytosine dioxygenases in mammalian development.

Zhao H, Chen T. Zhao H, et al. Among authors: chen t. J Hum Genet. 2013 Jul;58(7):421-7. doi: 10.1038/jhg.2013.63. Epub 2013 May 30. J Hum Genet. 2013. PMID: 23719188 Free PMC article. Review.

4

Genetic alterations of DNA methylation machinery in human diseases.

Hamidi T, Singh AK, Chen T. Hamidi T, et al. Among authors: chen t. Epigenomics. 2015;7(2):247-65. doi: 10.2217/epi.14.80. Epigenomics. 2015. PMID: 25942534 Review.

5

LSD1 is essential for oocyte meiotic progression by regulating CDC25B expression in mice.

Kim J, Singh AK, Takata Y, Lin K, Shen J, Lu Y, Kerenyi MA, Orkin SH, Chen T. Kim J, et al. Among authors: chen t. Nat Commun. 2015 Dec 2;6:10116. doi: 10.1038/ncomms10116. Nat Commun. 2015. PMID: 26626423 Free PMC article.

6

Maternal Setdb1 Is Required for Meiotic Progression and Preimplantation Development in Mouse.

Kim J, Zhao H, Dan J, Kim S, Hardikar S, Hollowell D, Lin K, Lu Y, Takata Y, Shen J, Chen T. Kim J, et al. Among authors: chen t. PLoS Genet. 2016 Apr 12;12(4):e1005970. doi: 10.1371/journal.pgen.1005970. eCollection 2016 Apr. PLoS Genet. 2016. PMID: 27070551 Free PMC article.

7

Zscan4 Inhibits Maintenance DNA Methylation to Facilitate Telomere Elongation in Mouse Embryonic Stem Cells.

Dan J, Rousseau P, Hardikar S, Veland N, Wong J, Autexier C, Chen T. Dan J, et al. Among authors: chen t. Cell Rep. 2017 Aug 22;20(8):1936-1949. doi: 10.1016/j.celrep.2017.07.070. Cell Rep. 2017. PMID: 28834755 Free PMC article.

8

The Arginine Methyltransferase PRMT6 Regulates DNA Methylation and Contributes to Global DNA Hypomethylation in Cancer.

Veland N, Hardikar S, Zhong Y, Gayatri S, Dan J, Strahl BD, Rothbart SB, Bedford MT, Chen T. Veland N, et al. Among authors: chen t. Cell Rep. 2017 Dec 19;21(12):3390-3397. doi: 10.1016/j.celrep.2017.11.082. Cell Rep. 2017. PMID: 29262320 Free PMC article.

9

Identification of Rpl29 as a major substrate of the lysine methyltransferase Set7/9.

Hamidi T, Singh AK, Veland N, Vemulapalli V, Chen J, Hardikar S, Bao J, Fry CJ, Yang V, Lee KA, Guo A, Arrowsmith CH, Bedford MT, Chen T. Hamidi T, et al. Among authors: chen j, chen t. J Biol Chem. 2018 Aug 17;293(33):12770-12780. doi: 10.1074/jbc.RA118.002890. Epub 2018 Jun 29. J Biol Chem. 2018. PMID: 29959229 Free PMC article.

10

DNMT3A and TET1 cooperate to regulate promoter epigenetic landscapes in mouse embryonic stem cells.

Gu T, Lin X, Cullen SM, Luo M, Jeong M, Estecio M, Shen J, Hardikar S, Sun D, Su J, Rux D, Guzman A, Lee M, Qi LS, Chen JJ, Kyba M, Huang Y, Chen T, Li W, Goodell MA. Gu T, et al. Among authors: chen jj, chen t. Genome Biol. 2018 Jul 12;19(1):88. doi: 10.1186/s13059-018-1464-7. Genome Biol. 2018. PMID: 30001199 Free PMC article.

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