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Sin1 phosphorylation impairs mTORC2 complex integrity and inhibits downstream Akt signalling to suppress tumorigenesis.
Liu P, Gan W, Inuzuka H, Lazorchak AS, Gao D, Arojo O, Liu D, Wan L, Zhai B, Yu Y, Yuan M, Kim BM, Shaik S, Menon S, Gygi SP, Lee TH, Asara JM, Manning BD, Blenis J, Su B, Wei W. Liu P, et al. Among authors: liu d. Nat Cell Biol. 2013 Nov;15(11):1340-50. doi: 10.1038/ncb2860. Epub 2013 Oct 27. Nat Cell Biol. 2013. PMID: 24161930 Free PMC article.
Mcl-1 ubiquitination and destruction.
Inuzuka H, Fukushima H, Shaik S, Liu P, Lau AW, Wei W. Inuzuka H, et al. Among authors: liu p. Oncotarget. 2011 Mar;2(3):239-44. doi: 10.18632/oncotarget.242. Oncotarget. 2011. PMID: 21608150 Free PMC article. Review.
Skp2: a novel potential therapeutic target for prostate cancer.
Wang Z, Gao D, Fukushima H, Inuzuka H, Liu P, Wan L, Sarkar FH, Wei W. Wang Z, et al. Among authors: liu p. Biochim Biophys Acta. 2012 Jan;1825(1):11-7. doi: 10.1016/j.bbcan.2011.09.002. Epub 2011 Sep 22. Biochim Biophys Acta. 2012. PMID: 21963805 Free PMC article. Review.
The two faces of FBW7 in cancer drug resistance.
Wang Z, Fukushima H, Gao D, Inuzuka H, Wan L, Lau AW, Liu P, Wei W. Wang Z, et al. Among authors: liu p. Bioessays. 2011 Nov;33(11):851-9. doi: 10.1002/bies.201100101. Epub 2011 Aug 30. Bioessays. 2011. PMID: 22006825 Free PMC article. Review.
Skp2 is a promising therapeutic target in breast cancer.
Wang Z, Fukushima H, Inuzuka H, Wan L, Liu P, Gao D, Sarkar FH, Wei W. Wang Z, et al. Among authors: liu p. Front Oncol. 2012 Jan 4;1(57):57. doi: 10.3389/fonc.2011.00057. Front Oncol. 2012. PMID: 22279619 Free PMC article.
DEPTOR ubiquitination and destruction by SCF(β-TrCP).
Wang Z, Zhong J, Gao D, Inuzuka H, Liu P, Wei W. Wang Z, et al. Among authors: liu p. Am J Physiol Endocrinol Metab. 2012 Jul 15;303(2):E163-9. doi: 10.1152/ajpendo.00105.2012. Epub 2012 Mar 27. Am J Physiol Endocrinol Metab. 2012. PMID: 22454292 Free PMC article. Review.
Cdc20: a potential novel therapeutic target for cancer treatment.
Wang Z, Wan L, Zhong J, Inuzuka H, Liu P, Sarkar FH, Wei W. Wang Z, et al. Among authors: liu p. Curr Pharm Des. 2013;19(18):3210-4. doi: 10.2174/1381612811319180005. Curr Pharm Des. 2013. PMID: 23151139 Free PMC article. Review.
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