Gao D - Search Results

1

Sin1 phosphorylation impairs mTORC2 complex integrity and inhibits downstream Akt signalling to suppress tumorigenesis.

Liu P, Gan W, Inuzuka H, Lazorchak AS, Gao D, Arojo O, Liu D, Wan L, Zhai B, Yu Y, Yuan M, Kim BM, Shaik S, Menon S, Gygi SP, Lee TH, Asara JM, Manning BD, Blenis J, Su B, Wei W. Liu P, et al. Among authors: gao d. Nat Cell Biol. 2013 Nov;15(11):1340-50. doi: 10.1038/ncb2860. Epub 2013 Oct 27. Nat Cell Biol. 2013. PMID: 24161930 Free PMC article.

2

Experimental approaches to investigate the proteasomal degradation pathways involved in regulation of apoptosis.

Tseng A, Inuzuka H, Gao D, Singh A, Wei W. Tseng A, et al. Among authors: gao d. Methods Enzymol. 2008;446:205-23. doi: 10.1016/S0076-6879(08)01612-1. Methods Enzymol. 2008. PMID: 18603124

3

Phosphorylation by Akt1 promotes cytoplasmic localization of Skp2 and impairs APCCdh1-mediated Skp2 destruction.

Gao D, Inuzuka H, Tseng A, Chin RY, Toker A, Wei W. Gao D, et al. Nat Cell Biol. 2009 Apr;11(4):397-408. doi: 10.1038/ncb1847. Epub 2009 Mar 8. Nat Cell Biol. 2009. PMID: 19270695 Free PMC article.

4

Cdh1 regulates cell cycle through modulating the claspin/Chk1 and the Rb/E2F1 pathways.

Gao D, Inuzuka H, Korenjak M, Tseng A, Wu T, Wan L, Kirschner M, Dyson N, Wei W. Gao D, et al. Mol Biol Cell. 2009 Jul;20(14):3305-16. doi: 10.1091/mbc.e09-01-0092. Epub 2009 May 28. Mol Biol Cell. 2009. PMID: 19477924 Free PMC article.

5

Akt finds its new path to regulate cell cycle through modulating Skp2 activity and its destruction by APC/Cdh1.

Gao D, Inuzuka H, Tseng A, Wei W. Gao D, et al. Cell Div. 2009 Jun 23;4:11. doi: 10.1186/1747-1028-4-11. Cell Div. 2009. PMID: 19549334 Free PMC article.

6

Protein phosphatase 2A reactivates FOXO3a through a dynamic interplay with 14-3-3 and AKT.

Singh A, Ye M, Bucur O, Zhu S, Tanya Santos M, Rabinovitz I, Wei W, Gao D, Hahn WC, Khosravi-Far R. Singh A, et al. Among authors: gao d. Mol Biol Cell. 2010 Mar 15;21(6):1140-52. doi: 10.1091/mbc.e09-09-0795. Epub 2010 Jan 28. Mol Biol Cell. 2010. PMID: 20110348 Free PMC article.

7

Phosphorylation by casein kinase I promotes the turnover of the Mdm2 oncoprotein via the SCF(beta-TRCP) ubiquitin ligase.

Inuzuka H, Tseng A, Gao D, Zhai B, Zhang Q, Shaik S, Wan L, Ang XL, Mock C, Yin H, Stommel JM, Gygi S, Lahav G, Asara J, Xiao ZX, Kaelin WG Jr, Harper JW, Wei W. Inuzuka H, et al. Among authors: gao d. Cancer Cell. 2010 Aug 9;18(2):147-59. doi: 10.1016/j.ccr.2010.06.015. Cancer Cell. 2010. PMID: 20708156 Free PMC article.

8

Rictor forms a complex with Cullin-1 to promote SGK1 ubiquitination and destruction.

Gao D, Wan L, Inuzuka H, Berg AH, Tseng A, Zhai B, Shaik S, Bennett E, Tron AE, Gasser JA, Lau A, Gygi SP, Harper JW, DeCaprio JA, Toker A, Wei W. Gao D, et al. Mol Cell. 2010 Sep 10;39(5):797-808. doi: 10.1016/j.molcel.2010.08.016. Mol Cell. 2010. PMID: 20832730 Free PMC article.

9

Phosphorylation of Rictor at Thr1135 impairs the Rictor/Cullin-1 complex to ubiquitinate SGK1.

Gao D, Wan L, Wei W. Gao D, et al. Protein Cell. 2010 Oct;1(10):881-5. doi: 10.1007/s13238-010-0123-x. Protein Cell. 2010. PMID: 21204013 Free PMC article.

10

SCF(FBW7) regulates cellular apoptosis by targeting MCL1 for ubiquitylation and destruction.

Inuzuka H, Shaik S, Onoyama I, Gao D, Tseng A, Maser RS, Zhai B, Wan L, Gutierrez A, Lau AW, Xiao Y, Christie AL, Aster J, Settleman J, Gygi SP, Kung AL, Look T, Nakayama KI, DePinho RA, Wei W. Inuzuka H, et al. Among authors: gao d. Nature. 2011 Mar 3;471(7336):104-9. doi: 10.1038/nature09732. Nature. 2011. PMID: 21368833 Free PMC article.

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