Niewoehner O - Search Results

1

Evolution of CRISPR RNA recognition and processing by Cas6 endonucleases.

Niewoehner O, Jinek M, Doudna JA. Niewoehner O, et al. Nucleic Acids Res. 2014 Jan;42(2):1341-53. doi: 10.1093/nar/gkt922. Epub 2013 Oct 22. Nucleic Acids Res. 2014. PMID: 24150936 Free PMC article.

2

In Vitro Reconstitution and Crystallization of Cas9 Endonuclease Bound to a Guide RNA and a DNA Target.

Anders C, Niewoehner O, Jinek M. Anders C, et al. Among authors: niewoehner o. Methods Enzymol. 2015;558:515-537. doi: 10.1016/bs.mie.2015.02.008. Epub 2015 Mar 12. Methods Enzymol. 2015. PMID: 26068752 Free PMC article.

3

Structural basis for the endoribonuclease activity of the type III-A CRISPR-associated protein Csm6.

Niewoehner O, Jinek M. Niewoehner O, et al. RNA. 2016 Mar;22(3):318-29. doi: 10.1261/rna.054098.115. Epub 2016 Jan 13. RNA. 2016. PMID: 26763118 Free PMC article.

4

Type III CRISPR-Cas systems produce cyclic oligoadenylate second messengers.

Niewoehner O, Garcia-Doval C, Rostøl JT, Berk C, Schwede F, Bigler L, Hall J, Marraffini LA, Jinek M. Niewoehner O, et al. Nature. 2017 Aug 31;548(7669):543-548. doi: 10.1038/nature23467. Epub 2017 Jul 19. Nature. 2017. PMID: 28722012

5

Specialized Weaponry: How a Type III-A CRISPR-Cas System Excels at Combating Phages.

Niewoehner O, Jinek M. Niewoehner O, et al. Cell Host Microbe. 2017 Sep 13;22(3):258-259. doi: 10.1016/j.chom.2017.08.019. Cell Host Microbe. 2017. PMID: 28910631 Free article.

6

Activation and self-inactivation mechanisms of the cyclic oligoadenylate-dependent CRISPR ribonuclease Csm6.

Garcia-Doval C, Schwede F, Berk C, Rostøl JT, Niewoehner O, Tejero O, Hall J, Marraffini LA, Jinek M. Garcia-Doval C, et al. Among authors: niewoehner o. Nat Commun. 2020 Mar 27;11(1):1596. doi: 10.1038/s41467-020-15334-5. Nat Commun. 2020. PMID: 32221291 Free PMC article.

7

Structural basis of PAM-dependent target DNA recognition by the Cas9 endonuclease.

Anders C, Niewoehner O, Duerst A, Jinek M. Anders C, et al. Among authors: niewoehner o. Nature. 2014 Sep 25;513(7519):569-73. doi: 10.1038/nature13579. Epub 2014 Jul 27. Nature. 2014. PMID: 25079318 Free PMC article.

8

Identification of the HECT E3 ligase UBR5 as a regulator of MYC degradation using a CRISPR/Cas9 screen.

Schukur L, Zimmermann T, Niewoehner O, Kerr G, Gleim S, Bauer-Probst B, Knapp B, Galli GG, Liang X, Mendiola A, Reece-Hoyes J, Rapti M, Barbosa I, Reschke M, Radimerski T, Thoma CR. Schukur L, et al. Among authors: niewoehner o. Sci Rep. 2020 Nov 18;10(1):20044. doi: 10.1038/s41598-020-76960-z. Sci Rep. 2020. PMID: 33208877 Free PMC article.

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