Beerli C - Search Results

1

Pharmacokinetics, biocompatibility and bioavailability of a controlled release monoclonal antibody formulation.

Schweizer D, Vostiar I, Heier A, Serno T, Schoenhammer K, Jahn M, Jones S, Piequet A, Beerli C, Gram H, Goepferich A. Schweizer D, et al. Among authors: beerli c. J Control Release. 2013 Dec 28;172(3):975-82. doi: 10.1016/j.jconrel.2013.10.010. Epub 2013 Oct 15. J Control Release. 2013. PMID: 24140353

2

Effects of the novel protein kinase C inhibitor AEB071 (Sotrastaurin) on rat cardiac allograft survival using single agent treatment or combination therapy with cyclosporine, everolimus or FTY720.

Weckbecker G, Pally C, Beerli C, Burkhart C, Wieczorek G, Metzler B, Morris RE, Wagner J, Bruns C. Weckbecker G, et al. Among authors: beerli c. Transpl Int. 2010 May 1;23(5):543-52. doi: 10.1111/j.1432-2277.2009.01015.x. Epub 2009 Dec 9. Transpl Int. 2010. PMID: 20003043 Free article.

3

Sotrastaurin (AEB071) alone and in combination with cyclosporine A prolongs survival times of non-human primate recipients of life-supporting kidney allografts.

Bigaud M, Wieczorek G, Beerli C, Audet M, Blancher A, Heusser C, Morris RE, Wagner J. Bigaud M, et al. Among authors: beerli c. Transplantation. 2012 Jan 27;93(2):156-64. doi: 10.1097/TP.0b013e31823cf92f. Transplantation. 2012. PMID: 22179400

4

Cellular assay for the characterization of sphingosine-1-phosphate lyase inhibitors.

Billich A, Beerli C, Bergmann R, Bruns C, Loetscher E. Billich A, et al. Among authors: beerli c. Anal Biochem. 2013 Mar 15;434(2):247-53. doi: 10.1016/j.ab.2012.11.026. Epub 2012 Dec 13. Anal Biochem. 2013. PMID: 23246729

5

Assay to measure the secretion of sphingosine-1-phosphate from cells induced by S1P lyase inhibitors.

Loetscher E, Schneider K, Beerli C, Billich A. Loetscher E, et al. Among authors: beerli c. Biochem Biophys Res Commun. 2013 Apr 12;433(3):345-8. doi: 10.1016/j.bbrc.2013.03.004. Epub 2013 Mar 14. Biochem Biophys Res Commun. 2013. PMID: 23499842

6

Orally active 7-substituted (4-benzylphthalazin-1-yl)-2-methylpiperazin-1-yl]nicotinonitriles as active-site inhibitors of sphingosine 1-phosphate lyase for the treatment of multiple sclerosis.

Weiler S, Braendlin N, Beerli C, Bergsdorf C, Schubart A, Srinivas H, Oberhauser B, Billich A. Weiler S, et al. Among authors: beerli c. J Med Chem. 2014 Jun 26;57(12):5074-84. doi: 10.1021/jm500338n. Epub 2014 May 21. J Med Chem. 2014. PMID: 24809814

7

An oral sphingosine 1-phosphate receptor 1 (S1P(1)) antagonist prodrug with efficacy in vivo: discovery, synthesis, and evaluation.

Angst D, Janser P, Quancard J, Buehlmayer P, Berst F, Oberer L, Beerli C, Streiff M, Pally C, Hersperger R, Bruns C, Bassilana F, Bollbuck B. Angst D, et al. Among authors: beerli c. J Med Chem. 2012 Nov 26;55(22):9722-34. doi: 10.1021/jm3009508. Epub 2012 Oct 26. J Med Chem. 2012. PMID: 23067318

8

Aromatic quinolinecarboxamides as selective, orally active antibody production inhibitors for prevention of acute xenograft rejection.

Papageorgiou C, von Matt A, Joergensen J, Andersen E, Wagner K, Beerli C, Than T, Borer X, Florineth A, Rihs G, Schreier MH, Weckbecker G, Heusser C. Papageorgiou C, et al. Among authors: beerli c. J Med Chem. 2001 Jun 7;44(12):1986-92. doi: 10.1021/jm010822m. J Med Chem. 2001. PMID: 11384243

9

A monoselective sphingosine-1-phosphate receptor-1 agonist prevents allograft rejection in a stringent rat heart transplantation model.

Pan S, Mi Y, Pally C, Beerli C, Chen A, Guerini D, Hinterding K, Nuesslein-Hildesheim B, Tuntland T, Lefebvre S, Liu Y, Gao W, Chu A, Brinkmann V, Bruns C, Streiff M, Cannet C, Cooke N, Gray N. Pan S, et al. Among authors: beerli c. Chem Biol. 2006 Nov;13(11):1227-34. doi: 10.1016/j.chembiol.2006.09.017. Chem Biol. 2006. PMID: 17114004

10

Reduced cardiac side-effect potential by introduction of polar groups: discovery of NIBR-1282, an orally bioavailable CCR5 antagonist which is active in vivo.

Thoma G, Beerli C, Bigaud M, Bruns C, Cooke NG, Streiff MB, Zerwes HG. Thoma G, et al. Among authors: beerli c. Bioorg Med Chem Lett. 2008 Mar 15;18(6):2000-5. doi: 10.1016/j.bmcl.2008.01.108. Epub 2008 Feb 2. Bioorg Med Chem Lett. 2008. PMID: 18267361

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