Fernández-Capetillo O - Search Results

1

p21 suppresses inflammation and tumorigenesis on pRB-deficient stratified epithelia.

Saiz-Ladera C, Lara MF, Garín M, Ruiz S, Santos M, Lorz C, García-Escudero R, Martínez-Fernández M, Bravo A, Fernández-Capetillo O, Segrelles C, Paramio JM. Saiz-Ladera C, et al. Oncogene. 2014 Sep 11;33(37):4599-4612. doi: 10.1038/onc.2013.417. Epub 2013 Oct 14. Oncogene. 2014. PMID: 24121270 Free PMC article.

2

ATR signaling can drive cells into senescence in the absence of DNA breaks.

Toledo LI, Murga M, Gutierrez-Martinez P, Soria R, Fernandez-Capetillo O. Toledo LI, et al. Genes Dev. 2008 Feb 1;22(3):297-302. doi: 10.1101/gad.452308. Genes Dev. 2008. PMID: 18245444 Free PMC article.

3

Increased telomere fragility and fusions resulting from TRF1 deficiency lead to degenerative pathologies and increased cancer in mice.

Martínez P, Thanasoula M, Muñoz P, Liao C, Tejera A, McNees C, Flores JM, Fernández-Capetillo O, Tarsounas M, Blasco MA. Martínez P, et al. Genes Dev. 2009 Sep 1;23(17):2060-75. doi: 10.1101/gad.543509. Epub 2009 Aug 13. Genes Dev. 2009. PMID: 19679647 Free PMC article.

4

p27Kip1 stabilization is essential for the maintenance of cell cycle arrest in response to DNA damage.

Cuadrado M, Gutierrez-Martinez P, Swat A, Nebreda AR, Fernandez-Capetillo O. Cuadrado M, et al. Cancer Res. 2009 Nov 15;69(22):8726-32. doi: 10.1158/0008-5472.CAN-09-0729. Epub 2009 Oct 20. Cancer Res. 2009. PMID: 19843869 Free PMC article.

5

INK4a/ARF limits the expansion of cells suffering from replication stress.

Monasor A, Murga M, Lopez-Contreras AJ, Navas C, Gomez G, Pisano DG, Fernandez-Capetillo O. Monasor A, et al. Cell Cycle. 2013 Jun 15;12(12):1948-54. doi: 10.4161/cc.25017. Epub 2013 May 15. Cell Cycle. 2013. PMID: 23676215 Free PMC article.

6

The maternal side of Fanconi Anemia.

Ruiz S, Fernandez-Capetillo O. Ruiz S, et al. Mol Cell. 2014 Sep 18;55(6):803-804. doi: 10.1016/j.molcel.2014.08.029. Mol Cell. 2014. PMID: 25238193 Free article.

7

Limiting replication stress during somatic cell reprogramming reduces genomic instability in induced pluripotent stem cells.

Ruiz S, Lopez-Contreras AJ, Gabut M, Marion RM, Gutierrez-Martinez P, Bua S, Ramirez O, Olalde I, Rodrigo-Perez S, Li H, Marques-Bonet T, Serrano M, Blasco MA, Batada NN, Fernandez-Capetillo O. Ruiz S, et al. Nat Commun. 2015 Aug 21;6:8036. doi: 10.1038/ncomms9036. Nat Commun. 2015. PMID: 26292731 Free PMC article.

8

Reducing genomic instability in iPSCs.

Ruiz S, Fernandez-Capetillo O. Ruiz S, et al. Oncotarget. 2015 Oct 27;6(33):34045-6. doi: 10.18632/oncotarget.6212. Oncotarget. 2015. PMID: 26550804 Free PMC article. No abstract available.

9

A Genome-wide CRISPR Screen Identifies CDC25A as a Determinant of Sensitivity to ATR Inhibitors.

Ruiz S, Mayor-Ruiz C, Lafarga V, Murga M, Vega-Sendino M, Ortega S, Fernandez-Capetillo O. Ruiz S, et al. Mol Cell. 2016 Apr 21;62(2):307-313. doi: 10.1016/j.molcel.2016.03.006. Epub 2016 Apr 7. Mol Cell. 2016. PMID: 27067599 Free PMC article.

10

A p53-dependent response limits the viability of mammalian haploid cells.

Olbrich T, Mayor-Ruiz C, Vega-Sendino M, Gomez C, Ortega S, Ruiz S, Fernandez-Capetillo O. Olbrich T, et al. Proc Natl Acad Sci U S A. 2017 Aug 29;114(35):9367-9372. doi: 10.1073/pnas.1705133114. Epub 2017 Aug 14. Proc Natl Acad Sci U S A. 2017. PMID: 28808015 Free PMC article.

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