Hawkins RE - Search Results

1

CD3ζ-based chimeric antigen receptors mediate T cell activation via cis- and trans-signalling mechanisms: implications for optimization of receptor structure for adoptive cell therapy.

Bridgeman JS, Ladell K, Sheard VE, Miners K, Hawkins RE, Price DA, Gilham DE. Bridgeman JS, et al. Among authors: hawkins re. Clin Exp Immunol. 2014 Feb;175(2):258-67. doi: 10.1111/cei.12216. Clin Exp Immunol. 2014. PMID: 24116999 Free PMC article.

2

Development of a flow cytometric co-immunoprecipitation technique for the study of multiple protein-protein interactions and its application to T-cell receptor analysis.

Bridgeman JS, Blaylock M, Hawkins RE, Gilham DE. Bridgeman JS, et al. Among authors: hawkins re. Cytometry A. 2010 Apr;77(4):338-46. doi: 10.1002/cyto.a.20840. Cytometry A. 2010. PMID: 20033991 Free article.

3

Building better chimeric antigen receptors for adoptive T cell therapy.

Bridgeman JS, Hawkins RE, Hombach AA, Abken H, Gilham DE. Bridgeman JS, et al. Among authors: hawkins re. Curr Gene Ther. 2010 Apr;10(2):77-90. doi: 10.2174/156652310791111001. Curr Gene Ther. 2010. PMID: 20222863 Review.

4

The optimal antigen response of chimeric antigen receptors harboring the CD3zeta transmembrane domain is dependent upon incorporation of the receptor into the endogenous TCR/CD3 complex.

Bridgeman JS, Hawkins RE, Bagley S, Blaylock M, Holland M, Gilham DE. Bridgeman JS, et al. Among authors: hawkins re. J Immunol. 2010 Jun 15;184(12):6938-49. doi: 10.4049/jimmunol.0901766. Epub 2010 May 17. J Immunol. 2010. PMID: 20483753

5

Targeted immunotherapy of cancer with CAR T cells: achievements and challenges.

Lipowska-Bhalla G, Gilham DE, Hawkins RE, Rothwell DG. Lipowska-Bhalla G, et al. Among authors: hawkins re. Cancer Immunol Immunother. 2012 Jul;61(7):953-62. doi: 10.1007/s00262-012-1254-0. Epub 2012 Apr 22. Cancer Immunol Immunother. 2012. PMID: 22527245 Free PMC article. Review.

6

Differential role of Th1 and Th2 cytokines in autotoxicity driven by CD19-specific second-generation chimeric antigen receptor T cells in a mouse model.

Cheadle EJ, Sheard V, Rothwell DG, Bridgeman JS, Ashton G, Hanson V, Mansoor AW, Hawkins RE, Gilham DE. Cheadle EJ, et al. Among authors: hawkins re. J Immunol. 2014 Apr 15;192(8):3654-65. doi: 10.4049/jimmunol.1302148. Epub 2014 Mar 12. J Immunol. 2014. PMID: 24623129 Free article.

7

Ligation of the CD2 co-stimulatory receptor enhances IL-2 production from first-generation chimeric antigen receptor T cells.

Cheadle EJ, Rothwell DG, Bridgeman JS, Sheard VE, Hawkins RE, Gilham DE. Cheadle EJ, et al. Among authors: hawkins re. Gene Ther. 2012 Nov;19(11):1114-20. doi: 10.1038/gt.2011.192. Epub 2011 Dec 1. Gene Ther. 2012. PMID: 22130449

8

Adoptive T-cell therapy for cancer in the United kingdom: a review of activity for the British Society of Gene and Cell Therapy annual meeting 2015.

Gilham DE, Anderson J, Bridgeman JS, Hawkins RE, Exley MA, Stauss H, Maher J, Pule M, Sewell AK, Bendle G, Lee S, Qasim W, Thrasher A, Morris E. Gilham DE, et al. Among authors: hawkins re. Hum Gene Ther. 2015 May;26(5):276-85. doi: 10.1089/hum.2015.024. Hum Gene Ther. 2015. PMID: 25860661 Free PMC article. Review.

9

Engineering T-cells with antibody-based chimeric receptors for effective cancer therapy.

Thistlethwaite F, Mansoor W, Gilham DE, Hawkins RE. Thistlethwaite F, et al. Among authors: hawkins re. Curr Opin Mol Ther. 2005 Feb;7(1):48-55. Curr Opin Mol Ther. 2005. PMID: 15732529 Review.

10

Killing of non-Hodgkin lymphoma cells by autologous CD19 engineered T cells.

Cheadle EJ, Gilham DE, Thistlethwaite FC, Radford JA, Hawkins RE. Cheadle EJ, et al. Among authors: hawkins re. Br J Haematol. 2005 May;129(3):322-32. doi: 10.1111/j.1365-2141.2005.05456.x. Br J Haematol. 2005. PMID: 15842655 Free article.

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