Orkin SH - Search Results

1

An erythroid enhancer of BCL11A subject to genetic variation determines fetal hemoglobin level.

Bauer DE, Kamran SC, Lessard S, Xu J, Fujiwara Y, Lin C, Shao Z, Canver MC, Smith EC, Pinello L, Sabo PJ, Vierstra J, Voit RA, Yuan GC, Porteus MH, Stamatoyannopoulos JA, Lettre G, Orkin SH. Bauer DE, et al. Among authors: orkin sh. Science. 2013 Oct 11;342(6155):253-7. doi: 10.1126/science.1242088. Science. 2013. PMID: 24115442 Free PMC article.

2

An erythroid-specific DNA binding factor mediates increased gamma-globin expression in hereditary persistence of fetal hemoglobin (HPFH).

Martin DI, Orkin SH. Martin DI, et al. Among authors: orkin sh. Prog Clin Biol Res. 1989;316A:217-28. Prog Clin Biol Res. 1989. PMID: 2480608 No abstract available.

3

Regulation of globin gene expression in erythroid cells.

Orkin SH. Orkin SH. Eur J Biochem. 1995 Jul 15;231(2):271-81. doi: 10.1111/j.1432-1033.1995.tb20697.x. Eur J Biochem. 1995. PMID: 7635138 Free article. Review.

4

Regulation of the erythroid Kruppel-like factor (EKLF) gene promoter by the erythroid transcription factor GATA-1.

Crossley M, Tsang AP, Bieker JJ, Orkin SH. Crossley M, et al. Among authors: orkin sh. J Biol Chem. 1994 Jun 3;269(22):15440-4. J Biol Chem. 1994. PMID: 8195185 Free article.

5

Isolation and characterization of the cDNA encoding BKLF/TEF-2, a major CACCC-box-binding protein in erythroid cells and selected other cells.

Crossley M, Whitelaw E, Perkins A, Williams G, Fujiwara Y, Orkin SH. Crossley M, et al. Among authors: orkin sh. Mol Cell Biol. 1996 Apr;16(4):1695-705. doi: 10.1128/MCB.16.4.1695. Mol Cell Biol. 1996. PMID: 8657145 Free PMC article.

6

The T cell leukemia oncoprotein SCL/tal-1 is essential for development of all hematopoietic lineages.

Porcher C, Swat W, Rockwell K, Fujiwara Y, Alt FW, Orkin SH. Porcher C, et al. Among authors: orkin sh. Cell. 1996 Jul 12;86(1):47-57. doi: 10.1016/s0092-8674(00)80076-8. Cell. 1996. PMID: 8689686 Free article.

7

Silencing of human fetal globin expression is impaired in the absence of the adult beta-globin gene activator protein EKLF.

Perkins AC, Gaensler KM, Orkin SH. Perkins AC, et al. Among authors: orkin sh. Proc Natl Acad Sci U S A. 1996 Oct 29;93(22):12267-71. doi: 10.1073/pnas.93.22.12267. Proc Natl Acad Sci U S A. 1996. PMID: 8901569 Free PMC article.

8

Arrested development of embryonic red cell precursors in mouse embryos lacking transcription factor GATA-1.

Fujiwara Y, Browne CP, Cunniff K, Goff SC, Orkin SH. Fujiwara Y, et al. Among authors: orkin sh. Proc Natl Acad Sci U S A. 1996 Oct 29;93(22):12355-8. doi: 10.1073/pnas.93.22.12355. Proc Natl Acad Sci U S A. 1996. PMID: 8901585 Free PMC article.

9

A "knockdown" mutation created by cis-element gene targeting reveals the dependence of erythroid cell maturation on the level of transcription factor GATA-1.

McDevitt MA, Shivdasani RA, Fujiwara Y, Yang H, Orkin SH. McDevitt MA, et al. Among authors: orkin sh. Proc Natl Acad Sci U S A. 1997 Jun 24;94(13):6781-5. doi: 10.1073/pnas.94.13.6781. Proc Natl Acad Sci U S A. 1997. PMID: 9192642 Free PMC article.

10

An upstream, DNase I hypersensitive region of the hematopoietic-expressed transcription factor GATA-1 gene confers developmental specificity in transgenic mice.

McDevitt MA, Fujiwara Y, Shivdasani RA, Orkin SH. McDevitt MA, et al. Among authors: orkin sh. Proc Natl Acad Sci U S A. 1997 Jul 22;94(15):7976-81. doi: 10.1073/pnas.94.15.7976. Proc Natl Acad Sci U S A. 1997. PMID: 9223298 Free PMC article.

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