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p21 promotes sustained liver regeneration and hepatocarcinogenesis in chronic cholestatic liver injury.
Marhenke S, Buitrago-Molina LE, Endig J, Orlik J, Schweitzer N, Klett S, Longerich T, Geffers R, Sánchez Muñoz A, Dorrell C, Katz SF, Lechel A, Weng H, Krech T, Lehmann U, Dooley S, Rudolph KL, Manns MP, Vogel A. Marhenke S, et al. Among authors: geffers r. Gut. 2014 Sep;63(9):1501-12. doi: 10.1136/gutjnl-2013-304829. Epub 2013 Oct 3. Gut. 2014. PMID: 24092862
Testing the importance of p27 degradation by the SCFskp2 pathway in murine models of lung and colon cancer.
Timmerbeul I, Garrett-Engele CM, Kossatz U, Chen X, Firpo E, Grünwald V, Kamino K, Wilkens L, Lehmann U, Buer J, Geffers R, Kubicka S, Manns MP, Porter PL, Roberts JM, Malek NP. Timmerbeul I, et al. Among authors: geffers r. Proc Natl Acad Sci U S A. 2006 Sep 19;103(38):14009-14. doi: 10.1073/pnas.0606316103. Epub 2006 Sep 11. Proc Natl Acad Sci U S A. 2006. PMID: 16966613 Free PMC article.
Argyrin a reveals a critical role for the tumor suppressor protein p27(kip1) in mediating antitumor activities in response to proteasome inhibition.
Nickeleit I, Zender S, Sasse F, Geffers R, Brandes G, Sörensen I, Steinmetz H, Kubicka S, Carlomagno T, Menche D, Gütgemann I, Buer J, Gossler A, Manns MP, Kalesse M, Frank R, Malek NP. Nickeleit I, et al. Among authors: geffers r. Cancer Cell. 2008 Jul 8;14(1):23-35. doi: 10.1016/j.ccr.2008.05.016. Cancer Cell. 2008. PMID: 18598941 Free article.
Interferon-alpha-induced TRAIL on natural killer cells is associated with control of hepatitis C virus infection.
Stegmann KA, Björkström NK, Veber H, Ciesek S, Riese P, Wiegand J, Hadem J, Suneetha PV, Jaroszewicz J, Wang C, Schlaphoff V, Fytili P, Cornberg M, Manns MP, Geffers R, Pietschmann T, Guzmán CA, Ljunggren HG, Wedemeyer H. Stegmann KA, et al. Among authors: geffers r. Gastroenterology. 2010 May;138(5):1885-97. doi: 10.1053/j.gastro.2010.01.051. Epub 2010 Feb 2. Gastroenterology. 2010. PMID: 20334827
309 results