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Overexpression of synphilin-1 promotes clearance of soluble and misfolded alpha-synuclein without restoring the motor phenotype in aged A30P transgenic mice.
Casadei N, Pöhler AM, Tomás-Zapico C, Torres-Peraza J, Schwedhelm I, Witz A, Zamolo I, De Heer R, Spruijt B, Noldus LP, Klucken J, Lucas JJ, Kahle PJ, Krüger R, Riess O, Nuber S. Casadei N, et al. Among authors: torres peraza j. Hum Mol Genet. 2014 Feb 1;23(3):767-81. doi: 10.1093/hmg/ddt467. Epub 2013 Sep 24. Hum Mol Genet. 2014. PMID: 24064336
Age-dependent decline of motor neocortex but not hippocampal performance in heterozygous BDNF mice correlates with a decrease of cortical PSD-95 but an increase of hippocampal TrkB levels.
Carretón O, Giralt A, Torres-Peraza JF, Brito V, Lucas JJ, Ginés S, Canals JM, Alberch J. Carretón O, et al. Among authors: torres peraza jf. Exp Neurol. 2012 Oct;237(2):335-45. doi: 10.1016/j.expneurol.2012.06.033. Epub 2012 Jul 6. Exp Neurol. 2012. PMID: 22776425
The neuroprotective transcription factor ATF5 is decreased and sequestered into polyglutamine inclusions in Huntington's disease.
Hernández IH, Torres-Peraza J, Santos-Galindo M, Ramos-Morón E, Fernández-Fernández MR, Pérez-Álvarez MJ, Miranda-Vizuete A, Lucas JJ. Hernández IH, et al. Among authors: torres peraza j. Acta Neuropathol. 2017 Dec;134(6):839-850. doi: 10.1007/s00401-017-1770-2. Epub 2017 Aug 31. Acta Neuropathol. 2017. PMID: 28861715 Free article.
PH domain leucine-rich repeat protein phosphatase 1 contributes to maintain the activation of the PI3K/Akt pro-survival pathway in Huntington's disease striatum.
Saavedra A, García-Martínez JM, Xifró X, Giralt A, Torres-Peraza JF, Canals JM, Díaz-Hernández M, Lucas JJ, Alberch J, Pérez-Navarro E. Saavedra A, et al. Among authors: torres peraza jf. Cell Death Differ. 2010 Feb;17(2):324-35. doi: 10.1038/cdd.2009.127. Epub 2009 Sep 11. Cell Death Differ. 2010. PMID: 19745829
Suppressing aberrant GluN3A expression rescues synaptic and behavioral impairments in Huntington's disease models.
Marco S, Giralt A, Petrovic MM, Pouladi MA, Martínez-Turrillas R, Martínez-Hernández J, Kaltenbach LS, Torres-Peraza J, Graham RK, Watanabe M, Luján R, Nakanishi N, Lipton SA, Lo DC, Hayden MR, Alberch J, Wesseling JF, Pérez-Otaño I. Marco S, et al. Among authors: torres peraza j. Nat Med. 2013 Aug;19(8):1030-8. doi: 10.1038/nm.3246. Epub 2013 Jul 14. Nat Med. 2013. PMID: 23852340 Free PMC article.
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