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The new small-molecule mixed-lineage kinase 3 inhibitor URMC-099 is neuroprotective and anti-inflammatory in models of human immunodeficiency virus-associated neurocognitive disorders.
Marker DF, Tremblay MÈ, Puccini JM, Barbieri J, Gantz Marker MA, Loweth CJ, Muly EC, Lu SM, Goodfellow VS, Dewhurst S, Gelbard HA. Marker DF, et al. Among authors: dewhurst s. J Neurosci. 2013 Jun 12;33(24):9998-10010. doi: 10.1523/JNEUROSCI.0598-13.2013. J Neurosci. 2013. PMID: 23761895 Free PMC article.
MLK3 regulates fMLP-stimulated neutrophil motility.
Polesskaya O, Wong C, Lebron L, Chamberlain JM, Gelbard HA, Goodfellow V, Kim M, Daiss JL, Dewhurst S. Polesskaya O, et al. Among authors: dewhurst s. Mol Immunol. 2014 Apr;58(2):214-22. doi: 10.1016/j.molimm.2013.11.016. Epub 2014 Jan 3. Mol Immunol. 2014. PMID: 24389043 Free PMC article.
Ablation of mixed lineage kinase 3 (Mlk3) does not inhibit ototoxicity induced by acoustic trauma or aminoglycoside exposure.
Polesskaya O, Cunningham LL, Francis SP, Luebke AE, Zhu X, Collins D, Vasilyeva ON, Sahler J, Desmet EA, Gelbard HA, Maggirwar SB, Walton JP, Frisina RD Jr, Dewhurst S. Polesskaya O, et al. Among authors: dewhurst s. Hear Res. 2010 Dec 1;270(1-2):21-7. doi: 10.1016/j.heares.2010.10.008. Epub 2010 Oct 27. Hear Res. 2010. PMID: 20971179 Free PMC article.
Pharmacokinetic interactions of CEP-1347 and atazanavir in HIV-infected patients.
Ma Q, Gelbard HA, Maggirwar SB, Dewhurst S, Gendelman HE, Peterson DR, DiFrancesco R, Hochreiter JS, Morse GD, Schifitto G. Ma Q, et al. Among authors: dewhurst s. J Neurovirol. 2013 Jun;19(3):254-60. doi: 10.1007/s13365-013-0172-z. Epub 2013 Jun 5. J Neurovirol. 2013. PMID: 23737347 Free PMC article.
338 results