Turchi JJ - Search Results

1

Targeting SHP2 for EGFR inhibitor resistant non-small cell lung carcinoma.

Xu J, Zeng LF, Shen W, Turchi JJ, Zhang ZY. Xu J, et al. Among authors: turchi jj. Biochem Biophys Res Commun. 2013 Oct 4;439(4):586-90. doi: 10.1016/j.bbrc.2013.09.028. Epub 2013 Sep 13. Biochem Biophys Res Commun. 2013. PMID: 24041688 Free PMC article.

2

Exploring a structural protein-drug interactome for new therapeutics in lung cancer.

Peng X, Wang F, Li L, Bum-Erdene K, Xu D, Wang B, Sinn AA, Pollok KE, Sandusky GE, Li L, Turchi JJ, Jalal SI, Meroueh SO. Peng X, et al. Among authors: turchi jj. Mol Biosyst. 2014 Mar 4;10(3):581-91. doi: 10.1039/c3mb70503j. Epub 2014 Jan 9. Mol Biosyst. 2014. PMID: 24402119 Free PMC article.

3

Chemical inhibitor targeting the replication protein A-DNA interaction increases the efficacy of Pt-based chemotherapy in lung and ovarian cancer.

Mishra AK, Dormi SS, Turchi AM, Woods DS, Turchi JJ. Mishra AK, et al. Among authors: turchi am, turchi jj. Biochem Pharmacol. 2015 Jan 1;93(1):25-33. doi: 10.1016/j.bcp.2014.10.013. Epub 2014 Nov 4. Biochem Pharmacol. 2015. PMID: 25449597 Free PMC article.

4

DNA damage response (DDR) pathway engagement in cisplatin radiosensitization of non-small cell lung cancer.

Sears CR, Cooney SA, Chin-Sinex H, Mendonca MS, Turchi JJ. Sears CR, et al. Among authors: turchi jj. DNA Repair (Amst). 2016 Apr;40:35-46. doi: 10.1016/j.dnarep.2016.02.004. Epub 2016 Mar 3. DNA Repair (Amst). 2016. PMID: 26991853 Free PMC article.

5

Targeted inhibition of Replication Protein A reveals cytotoxic activity, synergy with chemotherapeutic DNA-damaging agents, and insight into cellular function.

Shuck SC, Turchi JJ. Shuck SC, et al. Among authors: turchi jj. Cancer Res. 2010 Apr 15;70(8):3189-98. doi: 10.1158/0008-5472.CAN-09-3422. Cancer Res. 2010. PMID: 20395205 Free PMC article.

6

Targeting ovarian tumor cell adhesion mediated by tissue transglutaminase.

Khanna M, Chelladurai B, Gavini A, Li L, Shao M, Courtney D, Turchi JJ, Matei D, Meroueh S. Khanna M, et al. Among authors: turchi jj. Mol Cancer Ther. 2011 Apr;10(4):626-36. doi: 10.1158/1535-7163.MCT-10-0912. Epub 2011 Feb 17. Mol Cancer Ther. 2011. PMID: 21330459

7

Novel irreversible small molecule inhibitors of replication protein A display single-agent activity and synergize with cisplatin.

Neher TM, Bodenmiller D, Fitch RW, Jalal SI, Turchi JJ. Neher TM, et al. Among authors: turchi jj. Mol Cancer Ther. 2011 Oct;10(10):1796-806. doi: 10.1158/1535-7163.MCT-11-0303. Epub 2011 Aug 16. Mol Cancer Ther. 2011. PMID: 21846830 Free PMC article.

8

Complex cisplatin-double strand break (DSB) lesions directly impair cellular non-homologous end-joining (NHEJ) independent of downstream damage response (DDR) pathways.

Sears CR, Turchi JJ. Sears CR, et al. Among authors: turchi jj. J Biol Chem. 2012 Jul 13;287(29):24263-72. doi: 10.1074/jbc.M112.344911. Epub 2012 May 23. J Biol Chem. 2012. PMID: 22621925 Free PMC article.

9

Extracellular tissue transglutaminase activates noncanonical NF-κB signaling and promotes metastasis in ovarian cancer.

Yakubov B, Chelladurai B, Schmitt J, Emerson R, Turchi JJ, Matei D. Yakubov B, et al. Among authors: turchi jj. Neoplasia. 2013 Jun;15(6):609-19. doi: 10.1593/neo.121878. Neoplasia. 2013. PMID: 23730209 Free PMC article.

10

The novel, small-molecule DNA methylation inhibitor SGI-110 as an ovarian cancer chemosensitizer.

Fang F, Munck J, Tang J, Taverna P, Wang Y, Miller DF, Pilrose J, Choy G, Azab M, Pawelczak KS, VanderVere-Carozza P, Wagner M, Lyons J, Matei D, Turchi JJ, Nephew KP. Fang F, et al. Among authors: turchi jj. Clin Cancer Res. 2014 Dec 15;20(24):6504-16. doi: 10.1158/1078-0432.CCR-14-1553. Epub 2014 Oct 14. Clin Cancer Res. 2014. PMID: 25316809 Free PMC article.

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