Robinson M - Search Results

1

Preclinical characterization of the novel hepatitis C virus NS3 protease inhibitor GS-9451.

Yang H, Robinson M, Corsa AC, Peng B, Cheng G, Tian Y, Wang Y, Pakdaman R, Shen M, Qi X, Mo H, Tay C, Krawczyk S, Sheng XC, Kim CU, Yang C, Delaney WE 4th. Yang H, et al. Among authors: robinson m. Antimicrob Agents Chemother. 2014;58(2):647-53. doi: 10.1128/AAC.00487-13. Epub 2013 Aug 12. Antimicrob Agents Chemother. 2014. PMID: 23939899 Free PMC article.

2

Novel hepatitis C virus reporter replicon cell lines enable efficient antiviral screening against genotype 1a.

Robinson M, Yang H, Sun SC, Peng B, Tian Y, Pagratis N, Greenstein AE, Delaney WE 4th. Robinson M, et al. Antimicrob Agents Chemother. 2010 Aug;54(8):3099-106. doi: 10.1128/AAC.00289-10. Epub 2010 Jun 1. Antimicrob Agents Chemother. 2010. PMID: 20516274 Free PMC article.

3

Preexisting drug-resistance mutations reveal unique barriers to resistance for distinct antivirals.

Robinson M, Tian Y, Delaney WE 4th, Greenstein AE. Robinson M, et al. Proc Natl Acad Sci U S A. 2011 Jun 21;108(25):10290-5. doi: 10.1073/pnas.1101515108. Epub 2011 Jun 6. Proc Natl Acad Sci U S A. 2011. PMID: 21646519 Free PMC article.

4

Screening of hepatitis C virus inhibitors using genotype 1a HCV replicon cell lines.

Robinson M, Tian Y, Pagratis N, Delaney WE 4th. Robinson M, et al. Curr Protoc Microbiol. 2011 Aug;Chapter 17:Unit17.7. doi: 10.1002/9780471729259.mc1707s22. Curr Protoc Microbiol. 2011. PMID: 21805689

5

Preclinical characterization of the novel HCV NS3 protease inhibitor GS-9256.

Yang H, Yang C, Wang Y, Rhodes G, Robinson M, Cheng G, Qi X, Mo H, Tian Y, Pakdaman R, Sheng XC, Kim CU, Delaney WE 4th. Yang H, et al. Among authors: robinson m. Antivir Ther. 2017;22(5):413-420. doi: 10.3851/IMP3132. Epub 2017 Jan 20. Antivir Ther. 2017. PMID: 28106531

6

Comparison of HCV NS3 protease and NS5B polymerase inhibitor activity in 1a, 1b and 2a replicons and 2a infectious virus.

Paulson MS, Yang H, Shih IH, Feng JY, Mabery EM, Robinson MF, Zhong W, Delaney WE 4th. Paulson MS, et al. Among authors: robinson mf. Antiviral Res. 2009 Aug;83(2):135-42. doi: 10.1016/j.antiviral.2009.04.003. Epub 2009 Apr 14. Antiviral Res. 2009. PMID: 19457562

7

Development of a robust luciferase reporter 1b/2a hepatitis C virus (HCV) for characterization of early stage HCV life cycle inhibitors.

Chan K, Robinson M, Yang H, Cornew S, Delaney Iv WE. Chan K, et al. Among authors: robinson m. Antiviral Res. 2013 Apr;98(1):85-92. doi: 10.1016/j.antiviral.2013.01.005. Epub 2013 Feb 1. Antiviral Res. 2013. PMID: 23376631

8

Novel mutations in a tissue culture-adapted hepatitis C virus strain improve infectious-virus stability and markedly enhance infection kinetics.

Pokrovskii MV, Bush CO, Beran RK, Robinson MF, Cheng G, Tirunagari N, Fenaux M, Greenstein AE, Zhong W, Delaney WE 4th, Paulson MS. Pokrovskii MV, et al. Among authors: robinson mf. J Virol. 2011 Apr;85(8):3978-85. doi: 10.1128/JVI.01760-10. Epub 2011 Feb 2. J Virol. 2011. PMID: 21289124 Free PMC article.

9

Optimization of Pharmacokinetics through Manipulation of Physicochemical Properties in a Series of HCV Inhibitors.

Lazerwith SE, Bahador G, Canales E, Cheng G, Chong L, Clarke MO, Doerffler E, Eisenberg EJ, Hayes J, Lu B, Liu Q, Matles M, Mertzman M, Mitchell ML, Morganelli P, Murray BP, Robinson M, Strickley RG, Tessler M, Tirunagari N, Wang J, Wang Y, Zhang JR, Zheng X, Zhong W, Watkins WJ. Lazerwith SE, et al. Among authors: robinson m. ACS Med Chem Lett. 2011 Aug 8;2(10):715-9. doi: 10.1021/ml200163b. eCollection 2011 Oct 13. ACS Med Chem Lett. 2011. PMID: 24900257 Free PMC article.

10

A major determinant of cyclophilin dependence and cyclosporine susceptibility of hepatitis C virus identified by a genetic approach.

Yang F, Robotham JM, Grise H, Frausto S, Madan V, Zayas M, Bartenschlager R, Robinson M, Greenstein AE, Nag A, Logan TM, Bienkiewicz E, Tang H. Yang F, et al. Among authors: robinson m. PLoS Pathog. 2010 Sep 23;6(9):e1001118. doi: 10.1371/journal.ppat.1001118. PLoS Pathog. 2010. PMID: 20886100 Free PMC article.

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