Falkenburg JH - Search Results

1

Myeloablative T cell-depleted alloSCT with early sequential prophylactic donor lymphocyte infusion is an efficient and safe post-remission treatment for adult ALL.

Eefting M, Halkes CJ, de Wreede LC, van Pelt CM, Kersting S, Marijt EW, von dem Borne PA, Willemze R, Veelken H, Falkenburg JH. Eefting M, et al. Among authors: falkenburg jh. Bone Marrow Transplant. 2014 Feb;49(2):287-91. doi: 10.1038/bmt.2013.111. Epub 2013 Aug 12. Bone Marrow Transplant. 2014. PMID: 23933760

2

Minor histocompatibility antigens as targets of graft-versus-leukemia reactions.

Falkenburg JH, Marijt WA, Heemskerk MH, Willemze R. Falkenburg JH, et al. Curr Opin Hematol. 2002 Nov;9(6):497-502. doi: 10.1097/00062752-200211000-00005. Curr Opin Hematol. 2002. PMID: 12394171 Review.

3

High susceptibility of human leukemic cells to Fas-induced apoptosis is restricted to G1 phase of the cell cycle and can be increased by interferon treatment.

Jedema I, Barge RM, Willemze R, Falkenburg JH. Jedema I, et al. Among authors: falkenburg jh. Leukemia. 2003 Mar;17(3):576-84. doi: 10.1038/sj.leu.2402844. Leukemia. 2003. PMID: 12646947

4

The progenitor cell inhibition assay to measure the anti-leukemic reactivity of T cell clones against acute and chronic myeloid leukemia.

van der Hoorn MA, van Luxemburg-Heijs SA, van Bergen CA, Bongaerts R, Willemze R, Falkenburg JH. van der Hoorn MA, et al. Among authors: falkenburg jh. Methods. 2003 Oct;31(2):113-9. doi: 10.1016/s1046-2023(03)00120-8. Methods. 2003. PMID: 12957568

5

Internalization and cell cycle-dependent killing of leukemic cells by Gemtuzumab Ozogamicin: rationale for efficacy in CD33-negative malignancies with endocytic capacity.

Jedema I, Barge RM, van der Velden VH, Nijmeijer BA, van Dongen JJ, Willemze R, Falkenburg JH. Jedema I, et al. Among authors: falkenburg jh. Leukemia. 2004 Feb;18(2):316-25. doi: 10.1038/sj.leu.2403205. Leukemia. 2004. PMID: 14614514

6

Direct cloning of leukemia-reactive T cells from patients treated with donor lymphocyte infusion shows a relative dominance of hematopoiesis-restricted minor histocompatibility antigen HA-1 and HA-2 specific T cells.

Kloosterboer FM, van Luxemburg-Heijs SA, van Soest RA, Barbui AM, van Egmond HM, Strijbosch MP, Kester MG, Marijt WA, Goulmy E, Willemze R, Falkenburg JH. Kloosterboer FM, et al. Among authors: falkenburg jh. Leukemia. 2004 Apr;18(4):798-808. doi: 10.1038/sj.leu.2403297. Leukemia. 2004. PMID: 14973499

7

Generation of B-cell chronic lymphocytic leukemia (B-CLL)-reactive T-cell lines and clones from HLA class I-matched donors using modified B-CLL cells as stimulators: implications for adoptive immunotherapy.

Hoogendoorn M, Wolbers JO, Smit WM, Schaafsma MR, Barge RM, Willemze R, Falkenburg JH. Hoogendoorn M, et al. Among authors: falkenburg jh. Leukemia. 2004 Jul;18(7):1278-87. doi: 10.1038/sj.leu.2403358. Leukemia. 2004. PMID: 15116118

8

Umbilical cord blood-naive T cells but not adult blood-naive T cells require HLA class II on antigen-presenting cells for allo-immune activation.

Kloosterboer FM, van Luxemburg-Heijs SA, Willemze R, Falkenburg JH. Kloosterboer FM, et al. Among authors: falkenburg jh. Hum Immunol. 2004 Apr;65(4):328-39. doi: 10.1016/j.humimm.2004.01.003. Hum Immunol. 2004. PMID: 15120187

9

Minor histocompatibility antigen-specific T cells with multiple distinct specificities can be isolated by direct cloning of IFNgamma-secreting T cells from patients with relapsed leukemia responding to donor lymphocyte infusion.

Kloosterboer FM, van Luxemburg-Heijs SA, van Soest RA, van Egmond HM, Barbui AM, Strijbosch MP, Willemze R, Falkenburg JH. Kloosterboer FM, et al. Among authors: falkenburg jh. Leukemia. 2005 Jan;19(1):83-90. doi: 10.1038/sj.leu.2403572. Leukemia. 2005. PMID: 15526024

10

HLA class II restricted T-cell receptor gene transfer generates CD4+ T cells with helper activity as well as cytotoxic capacity.

van der Veken LT, Hoogeboom M, de Paus RA, Willemze R, Falkenburg JH, Heemskerk MH. van der Veken LT, et al. Among authors: falkenburg jh. Gene Ther. 2005 Dec;12(23):1686-95. doi: 10.1038/sj.gt.3302586. Gene Ther. 2005. PMID: 16034453

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