Agar JN - Search Results

1

Structural consequences of cysteinylation of Cu/Zn-superoxide dismutase.

Auclair JR, Brodkin HR, D'Aquino JA, Petsko GA, Ringe D, Agar JN. Auclair JR, et al. Among authors: agar jn. Biochemistry. 2013 Sep 10;52(36):6145-50. doi: 10.1021/bi400613h. Epub 2013 Aug 26. Biochemistry. 2013. PMID: 23919400 Free PMC article.

2

A common property of amyotrophic lateral sclerosis-associated variants: destabilization of the copper/zinc superoxide dismutase electrostatic loop.

Molnar KS, Karabacak NM, Johnson JL, Wang Q, Tiwari A, Hayward LJ, Coales SJ, Hamuro Y, Agar JN. Molnar KS, et al. Among authors: agar jn. J Biol Chem. 2009 Nov 6;284(45):30965-73. doi: 10.1074/jbc.M109.023945. Epub 2009 Jul 27. J Biol Chem. 2009. PMID: 19635794 Free PMC article.

3

Strategies for stabilizing superoxide dismutase (SOD1), the protein destabilized in the most common form of familial amyotrophic lateral sclerosis.

Auclair JR, Boggio KJ, Petsko GA, Ringe D, Agar JN. Auclair JR, et al. Among authors: agar jn. Proc Natl Acad Sci U S A. 2010 Dec 14;107(50):21394-9. doi: 10.1073/pnas.1015463107. Epub 2010 Nov 22. Proc Natl Acad Sci U S A. 2010. PMID: 21098299 Free PMC article.

4

Evidence of the participation of remote residues in the catalytic activity of Co-type nitrile hydratase from Pseudomonas putida.

Brodkin HR, Novak WR, Milne AC, D'Aquino JA, Karabacak NM, Goldberg IG, Agar JN, Payne MS, Petsko GA, Ondrechen MJ, Ringe D. Brodkin HR, et al. Among authors: agar jn. Biochemistry. 2011 Jun 7;50(22):4923-35. doi: 10.1021/bi101761e. Epub 2011 May 12. Biochemistry. 2011. PMID: 21473592 Free PMC article.

5

A soluble α-synuclein construct forms a dynamic tetramer.

Wang W, Perovic I, Chittuluru J, Kaganovich A, Nguyen LT, Liao J, Auclair JR, Johnson D, Landeru A, Simorellis AK, Ju S, Cookson MR, Asturias FJ, Agar JN, Webb BN, Kang C, Ringe D, Petsko GA, Pochapsky TC, Hoang QQ. Wang W, et al. Among authors: agar jn. Proc Natl Acad Sci U S A. 2011 Oct 25;108(43):17797-802. doi: 10.1073/pnas.1113260108. Epub 2011 Oct 17. Proc Natl Acad Sci U S A. 2011. PMID: 22006323 Free PMC article.

6

Mass spectrometry tools for analysis of intermolecular interactions.

Auclair JR, Somasundaran M, Green KM, Evans JE, Schiffer CA, Ringe D, Petsko GA, Agar JN. Auclair JR, et al. Among authors: agar jn. Methods Mol Biol. 2012;896:387-98. doi: 10.1007/978-1-4614-3704-8_26. Methods Mol Biol. 2012. PMID: 22821539 Free PMC article.

7

Post-translational modification by cysteine protects Cu/Zn-superoxide dismutase from oxidative damage.

Auclair JR, Johnson JL, Liu Q, Salisbury JP, Rotunno MS, Petsko GA, Ringe D, Brown RH Jr, Bosco DA, Agar JN. Auclair JR, et al. Among authors: agar jn. Biochemistry. 2013 Sep 10;52(36):6137-44. doi: 10.1021/bi4006122. Epub 2013 Aug 26. Biochemistry. 2013. PMID: 23927036 Free PMC article.

8

Artifacts to avoid while taking advantage of top-down mass spectrometry based detection of protein S-thiolation.

Auclair JR, Salisbury JP, Johnson JL, Petsko GA, Ringe D, Bosco DA, Agar NY, Santagata S, Durham HD, Agar JN. Auclair JR, et al. Among authors: agar jn, agar ny. Proteomics. 2014 May;14(10):1152-7. doi: 10.1002/pmic.201300450. Epub 2014 Apr 17. Proteomics. 2014. PMID: 24634066 Free PMC article.

9

Identification of a misfolded region in superoxide dismutase 1 that is exposed in amyotrophic lateral sclerosis.

Rotunno MS, Auclair JR, Maniatis S, Shaffer SA, Agar J, Bosco DA. Rotunno MS, et al. J Biol Chem. 2014 Oct 10;289(41):28527-38. doi: 10.1074/jbc.M114.581801. Epub 2014 Aug 27. J Biol Chem. 2014. PMID: 25164820 Free PMC article.

10

The central nervous system transcriptome of the weakly electric brown ghost knifefish (Apteronotus leptorhynchus): de novo assembly, annotation, and proteomics validation.

Salisbury JP, Sîrbulescu RF, Moran BM, Auclair JR, Zupanc GK, Agar JN. Salisbury JP, et al. Among authors: agar jn. BMC Genomics. 2015 Mar 11;16(1):166. doi: 10.1186/s12864-015-1354-2. BMC Genomics. 2015. PMID: 25879418 Free PMC article.

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