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Epoxyeicosanoids promote organ and tissue regeneration.
Panigrahy D, Kalish BT, Huang S, Bielenberg DR, Le HD, Yang J, Edin ML, Lee CR, Benny O, Mudge DK, Butterfield CE, Mammoto A, Mammoto T, Inceoglu B, Jenkins RL, Simpson MA, Akino T, Lih FB, Tomer KB, Ingber DE, Hammock BD, Falck JR, Manthati VL, Kaipainen A, D'Amore PA, Puder M, Zeldin DC, Kieran MW. Panigrahy D, et al. Among authors: falck jr. Proc Natl Acad Sci U S A. 2013 Aug 13;110(33):13528-33. doi: 10.1073/pnas.1311565110. Epub 2013 Jul 29. Proc Natl Acad Sci U S A. 2013. PMID: 23898174 Free PMC article.
Epoxyeicosanoids stimulate multiorgan metastasis and tumor dormancy escape in mice.
Panigrahy D, Edin ML, Lee CR, Huang S, Bielenberg DR, Butterfield CE, Barnés CM, Mammoto A, Mammoto T, Luria A, Benny O, Chaponis DM, Dudley AC, Greene ER, Vergilio JA, Pietramaggiori G, Scherer-Pietramaggiori SS, Short SM, Seth M, Lih FB, Tomer KB, Yang J, Schwendener RA, Hammock BD, Falck JR, Manthati VL, Ingber DE, Kaipainen A, D'Amore PA, Kieran MW, Zeldin DC. Panigrahy D, et al. Among authors: falck jr. J Clin Invest. 2012 Jan;122(1):178-91. doi: 10.1172/JCI58128. Epub 2011 Dec 19. J Clin Invest. 2012. PMID: 22182838 Free PMC article.
Cytochrome P450 monooxygenase lipid metabolites are significant second messengers in the resolution of choroidal neovascularization.
Hasegawa E, Inafuku S, Mulki L, Okunuki Y, Yanai R, Smith KE, Kim CB, Klokman G, Bielenberg DR, Puli N, Falck JR, Husain D, Miller JW, Edin ML, Zeldin DC, Lee KSS, Hammock BD, Schunck WH, Connor KM. Hasegawa E, et al. Among authors: falck jr. Proc Natl Acad Sci U S A. 2017 Sep 5;114(36):E7545-E7553. doi: 10.1073/pnas.1620898114. Epub 2017 Aug 21. Proc Natl Acad Sci U S A. 2017. PMID: 28827330 Free PMC article.
Reduced coronary reactive hyperemia in mice was reversed by the soluble epoxide hydrolase inhibitor (t-AUCB): Role of adenosine A2A receptor and plasma oxylipins.
Hanif A, Edin ML, Zeldin DC, Morisseau C, Falck JR, Ledent C, Tilley SL, Nayeem MA. Hanif A, et al. Among authors: falck jr. Prostaglandins Other Lipid Mediat. 2017 Jul;131:83-95. doi: 10.1016/j.prostaglandins.2017.09.001. Epub 2017 Sep 7. Prostaglandins Other Lipid Mediat. 2017. PMID: 28890385 Free PMC article.
Endothelial expression of human cytochrome P450 epoxygenases lowers blood pressure and attenuates hypertension-induced renal injury in mice.
Lee CR, Imig JD, Edin ML, Foley J, DeGraff LM, Bradbury JA, Graves JP, Lih FB, Clark J, Myers P, Perrow AL, Lepp AN, Kannon MA, Ronnekleiv OK, Alkayed NJ, Falck JR, Tomer KB, Zeldin DC. Lee CR, et al. Among authors: falck jr. FASEB J. 2010 Oct;24(10):3770-81. doi: 10.1096/fj.10-160119. Epub 2010 May 21. FASEB J. 2010. PMID: 20495177 Free PMC article.
Epoxyeicosatrienoic and dihydroxyeicosatrienoic acids dilate human coronary arterioles via BK(Ca) channels: implications for soluble epoxide hydrolase inhibition.
Larsen BT, Miura H, Hatoum OA, Campbell WB, Hammock BD, Zeldin DC, Falck JR, Gutterman DD. Larsen BT, et al. Among authors: falck jr. Am J Physiol Heart Circ Physiol. 2006 Feb;290(2):H491-9. doi: 10.1152/ajpheart.00927.2005. Epub 2005 Oct 28. Am J Physiol Heart Circ Physiol. 2006. PMID: 16258029 Free PMC article.
Vascular characterization of mice with endothelial expression of cytochrome P450 4F2.
Cheng J, Edin ML, Hoopes SL, Li H, Bradbury JA, Graves JP, DeGraff LM, Lih FB, Garcia V, Shaik JS, Tomer KB, Flake GP, Falck JR, Lee CR, Poloyac SM, Schwartzman ML, Zeldin DC. Cheng J, et al. Among authors: falck jr. FASEB J. 2014 Jul;28(7):2915-31. doi: 10.1096/fj.13-241927. Epub 2014 Mar 25. FASEB J. 2014. PMID: 24668751 Free PMC article.
684 results