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FK506 activates BMPR2, rescues endothelial dysfunction, and reverses pulmonary hypertension.
Spiekerkoetter E, Tian X, Cai J, Hopper RK, Sudheendra D, Li CG, El-Bizri N, Sawada H, Haghighat R, Chan R, Haghighat L, de Jesus Perez V, Wang L, Reddy S, Zhao M, Bernstein D, Solow-Cordero DE, Beachy PA, Wandless TJ, Ten Dijke P, Rabinovitch M. Spiekerkoetter E, et al. Among authors: chan r. J Clin Invest. 2013 Aug;123(8):3600-13. doi: 10.1172/JCI65592. Epub 2013 Jul 15. J Clin Invest. 2013. PMID: 23867624 Free PMC article.
Reduced BMPR2 expression induces GM-CSF translation and macrophage recruitment in humans and mice to exacerbate pulmonary hypertension.
Sawada H, Saito T, Nickel NP, Alastalo TP, Glotzbach JP, Chan R, Haghighat L, Fuchs G, Januszyk M, Cao A, Lai YJ, Perez Vde J, Kim YM, Wang L, Chen PI, Spiekerkoetter E, Mitani Y, Gurtner GC, Sarnow P, Rabinovitch M. Sawada H, et al. Among authors: chan r. J Exp Med. 2014 Feb 10;211(2):263-80. doi: 10.1084/jem.20111741. Epub 2014 Jan 20. J Exp Med. 2014. PMID: 24446489 Free PMC article.
Clinical Characteristics and Treatment Outcomes in Unilateral Coats disease - a Global Collaborative Study.
Tsai ASH, Wang CT, Lee TC, Nagiel A, Matsunaga K, Harper CA 3rd, Wood EH, Kim SJ, Hwang S, Shapiro MJ, Blair MP, Toth CA, Valikodath N, Martinez-Castellanos MA, Trese MGJ, Capone A Jr, Drenser K, Tauqeer Z, Besirli CG, Eton E, Hartnett ME, Bair C, Kennedy B, Kusaka S, Mano F, Chang EY, Rao P, Hunt PJ, Walsh MK, Moore S, Sears JE, Abraham J, Schulgit M, Vagaggini T, Quiram PA, Vavvas D, Patel NA, Hoyek S, Chan RVP, Challa N, Mendel T, Dewan KS, Rogers DL, Amphornphruet A, Wu WC. Tsai ASH, et al. Among authors: chan rvp. Ophthalmol Retina. 2024 Nov 27:S2468-6530(24)00574-8. doi: 10.1016/j.oret.2024.11.017. Online ahead of print. Ophthalmol Retina. 2024. PMID: 39613161
Opportunities for System Neuroscience.
Chan RW, Edelman BJ, Tsang SY, Gao K, Yu AC. Chan RW, et al. Adv Neurobiol. 2024;41:247-253. doi: 10.1007/978-3-031-69188-1_10. Adv Neurobiol. 2024. PMID: 39589717 Review.
Cutaneous Dermatologic Manifestations of Cardiovascular Diseases: A Narrative Review.
Kaye AD, Islam RK, Tong VT, McKee E, Gonzales JJ, Rais MS, Watson AE, Haas CJ, Chan R, Palowsky Z, Islam KN, Shekoohi S, Varrassi G. Kaye AD, et al. Among authors: chan r. Cureus. 2024 Oct 24;16(10):e72336. doi: 10.7759/cureus.72336. eCollection 2024 Oct. Cureus. 2024. PMID: 39583483 Free PMC article. Review.
3,857 results