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240 results

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Page 1
Paracetamol reduces influenza-induced immunopathology in a mouse model of infection without compromising virus clearance or the generation of protective immunity.
Lauder SN, Taylor PR, Clark SR, Evans RL, Hindley JP, Smart K, Leach H, Kidd EJ, Broadley KJ, Jones SA, Wise MP, Godkin AJ, O'Donnell V, Gallimore AM. Lauder SN, et al. Among authors: smart k. Thorax. 2011 May;66(5):368-74. doi: 10.1136/thx.2010.150318. Epub 2011 Feb 10. Thorax. 2011. PMID: 21310755 Free PMC article.
T-cell trafficking facilitated by high endothelial venules is required for tumor control after regulatory T-cell depletion.
Hindley JP, Jones E, Smart K, Bridgeman H, Lauder SN, Ondondo B, Cutting S, Ladell K, Wynn KK, Withers D, Price DA, Ager A, Godkin AJ, Gallimore AM. Hindley JP, et al. Among authors: smart k. Cancer Res. 2012 Nov 1;72(21):5473-82. doi: 10.1158/0008-5472.CAN-12-1912. Epub 2012 Sep 7. Cancer Res. 2012. PMID: 22962270 Free PMC article.
Avidity of influenza-specific memory CD8+ T-cell populations decays over time compromising antiviral immunity.
Humphreys IR, Clement M, Marsden M, Ladell K, McLaren JE, Smart K, Hindley JP, Bridgeman HM, van den Berg HA, Price DA, Ager A, Wooldridge L, Godkin A, Gallimore AM. Humphreys IR, et al. Among authors: smart k. Eur J Immunol. 2012 Dec;42(12):3235-42. doi: 10.1002/eji.201242575. Epub 2012 Oct 16. Eur J Immunol. 2012. PMID: 22965681 Free PMC article.
Highly prevalent colorectal cancer-infiltrating LAP⁺ Foxp3⁻ T cells exhibit more potent immunosuppressive activity than Foxp3⁺ regulatory T cells.
Scurr M, Ladell K, Besneux M, Christian A, Hockey T, Smart K, Bridgeman H, Hargest R, Phillips S, Davies M, Price D, Gallimore A, Godkin A. Scurr M, et al. Among authors: smart k. Mucosal Immunol. 2014 Mar;7(2):428-39. doi: 10.1038/mi.2013.62. Epub 2013 Sep 25. Mucosal Immunol. 2014. PMID: 24064667 Free PMC article.
Progression of carcinogen-induced fibrosarcomas is associated with the accumulation of naïve CD4+ T cells via blood vessels and lymphatics.
Ondondo B, Jones E, Hindley J, Cutting S, Smart K, Bridgeman H, Matthews KK, Ladell K, Price DA, Jackson DG, Godkin A, Ager A, Gallimore A. Ondondo B, et al. Among authors: smart k. Int J Cancer. 2014 May 1;134(9):2156-67. doi: 10.1002/ijc.28556. Epub 2013 Nov 8. Int J Cancer. 2014. PMID: 24142504 Free PMC article.
Escalating regulation of 5T4-specific IFN-γ+ CD4+ T cells distinguishes colorectal cancer patients from healthy controls and provides a target for in vivo therapy.
Scurr M, Bloom A, Pembroke T, Srinivasan R, Brown C, Smart K, Bridgeman H, Davies M, Hargest R, Phillips S, Christian A, Hockey T, Gallimore A, Godkin A. Scurr M, et al. Among authors: smart k. Cancer Immunol Res. 2013 Dec;1(6):10.1158/2326-6066.CIR-13-0035. doi: 10.1158/2326-6066.CIR-13-0035. Cancer Immunol Res. 2013. PMID: 24409450 Free PMC article.
Eliminating roles for T-bet and IL-2 but revealing superior activation and proliferation as mechanisms underpinning dominance of regulatory T cells in tumors.
Colbeck EJ, Hindley JP, Smart K, Jones E, Bloom A, Bridgeman H, McPherson RC, Turner DG, Ladell K, Price DA, O'Connor RA, Anderton SM, Godkin AJ, Gallimore AM. Colbeck EJ, et al. Among authors: smart k. Oncotarget. 2015 Sep 22;6(28):24649-59. doi: 10.18632/oncotarget.5584. Oncotarget. 2015. PMID: 26433463 Free PMC article.
Low-Dose Cyclophosphamide Induces Antitumor T-Cell Responses, which Associate with Survival in Metastatic Colorectal Cancer.
Scurr M, Pembroke T, Bloom A, Roberts D, Thomson A, Smart K, Bridgeman H, Adams R, Brewster A, Jones R, Gwynne S, Blount D, Harrop R, Hills R, Gallimore A, Godkin A. Scurr M, et al. Among authors: smart k. Clin Cancer Res. 2017 Nov 15;23(22):6771-6780. doi: 10.1158/1078-0432.CCR-17-0895. Epub 2017 Aug 29. Clin Cancer Res. 2017. PMID: 28855352 Free PMC article. Clinical Trial.
240 results