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Oncogenic targeting of BRM drives malignancy through C/EBPβ-dependent induction of α5 integrin.
Damiano L, Stewart KM, Cohet N, Mouw JK, Lakins JN, Debnath J, Reisman D, Nickerson JA, Imbalzano AN, Weaver VM. Damiano L, et al. Among authors: lakins jn. Oncogene. 2014 May 8;33(19):2441-53. doi: 10.1038/onc.2013.220. Epub 2013 Jun 17. Oncogene. 2014. Retraction in: Oncogene. 2024 Mar;43(14):1076. doi: 10.1038/s41388-024-02964-y. PMID: 23770848 Free PMC article. Retracted.
Integrin-mediated traction force enhances paxillin molecular associations and adhesion dynamics that increase the invasiveness of tumor cells into a three-dimensional extracellular matrix.
Mekhdjian AH, Kai F, Rubashkin MG, Prahl LS, Przybyla LM, McGregor AL, Bell ES, Barnes JM, DuFort CC, Ou G, Chang AC, Cassereau L, Tan SJ, Pickup MW, Lakins JN, Ye X, Davidson MW, Lammerding J, Odde DJ, Dunn AR, Weaver VM. Mekhdjian AH, et al. Among authors: lakins jn. Mol Biol Cell. 2017 Jun 1;28(11):1467-1488. doi: 10.1091/mbc.E16-09-0654. Epub 2017 Apr 5. Mol Biol Cell. 2017. PMID: 28381423 Free PMC article.
Antisecretory Factor-Mediated Inhibition of Cell Volume Dynamics Produces Antitumor Activity in Glioblastoma.
Ilkhanizadeh S, Sabelström H, Miroshnikova YA, Frantz A, Zhu W, Idilli A, Lakins JN, Schmidt C, Quigley DA, Fenster T, Yuan E, Trzeciak JR, Saxena S, Lindberg OR, Mouw JK, Burdick JA, Magnitsky S, Berger MS, Phillips JJ, Arosio D, Sun D, Weaver VM, Weiss WA, Persson AI. Ilkhanizadeh S, et al. Among authors: lakins jn. Mol Cancer Res. 2018 May;16(5):777-790. doi: 10.1158/1541-7786.MCR-17-0413. Epub 2018 Feb 5. Mol Cancer Res. 2018. PMID: 29431617 Free PMC article.
Low lamin A levels enhance confined cell migration and metastatic capacity in breast cancer.
Bell ES, Shah P, Zuela-Sopilniak N, Kim D, Varlet AA, Morival JLP, McGregor AL, Isermann P, Davidson PM, Elacqua JJ, Lakins JN, Vahdat L, Weaver VM, Smolka MB, Span PN, Lammerding J. Bell ES, et al. Among authors: lakins jn. Oncogene. 2022 Sep;41(36):4211-4230. doi: 10.1038/s41388-022-02420-9. Epub 2022 Jul 27. Oncogene. 2022. PMID: 35896617 Free PMC article.
41 results