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Overexpression of pendrin in intercalated cells produces chloride-sensitive hypertension.
Jacques T, Picard N, Miller RL, Riemondy KA, Houillier P, Sohet F, Ramakrishnan SK, Büsst CJ, Jayat M, Cornière N, Hassan H, Aronson PS, Hennings JC, Hübner CA, Nelson RD, Chambrey R, Eladari D. Jacques T, et al. Among authors: eladari d. J Am Soc Nephrol. 2013 Jun;24(7):1104-13. doi: 10.1681/ASN.2012080787. Epub 2013 Jun 13. J Am Soc Nephrol. 2013. PMID: 23766534 Free PMC article.
Pendrin regulation in mouse kidney primarily is chloride-dependent.
Vallet M, Picard N, Loffing-Cueni D, Fysekidis M, Bloch-Faure M, Deschênes G, Breton S, Meneton P, Loffing J, Aronson PS, Chambrey R, Eladari D. Vallet M, et al. Among authors: eladari d. J Am Soc Nephrol. 2006 Aug;17(8):2153-63. doi: 10.1681/ASN.2005101054. Epub 2006 Jul 6. J Am Soc Nephrol. 2006. PMID: 16825334
Renal intercalated cells are rather energized by a proton than a sodium pump.
Chambrey R, Kurth I, Peti-Peterdi J, Houillier P, Purkerson JM, Leviel F, Hentschke M, Zdebik AA, Schwartz GJ, Hübner CA, Eladari D. Chambrey R, et al. Among authors: eladari d. Proc Natl Acad Sci U S A. 2013 May 7;110(19):7928-33. doi: 10.1073/pnas.1221496110. Epub 2013 Apr 22. Proc Natl Acad Sci U S A. 2013. PMID: 23610411 Free PMC article.
Double Knockout of the Na+-Driven Cl-/HCO3- Exchanger and Na+/Cl- Cotransporter Induces Hypokalemia and Volume Depletion.
Sinning A, Radionov N, Trepiccione F, López-Cayuqueo KI, Jayat M, Baron S, Cornière N, Alexander RT, Hadchouel J, Eladari D, Hübner CA, Chambrey R. Sinning A, et al. Among authors: eladari d. J Am Soc Nephrol. 2017 Jan;28(1):130-139. doi: 10.1681/ASN.2015070734. Epub 2016 May 5. J Am Soc Nephrol. 2017. PMID: 27151921 Free PMC article.
The ClC-K2 Chloride Channel Is Critical for Salt Handling in the Distal Nephron.
Hennings JC, Andrini O, Picard N, Paulais M, Huebner AK, Cayuqueo IK, Bignon Y, Keck M, Cornière N, Böhm D, Jentsch TJ, Chambrey R, Teulon J, Hübner CA, Eladari D. Hennings JC, et al. Among authors: eladari d. J Am Soc Nephrol. 2017 Jan;28(1):209-217. doi: 10.1681/ASN.2016010085. Epub 2016 Jun 22. J Am Soc Nephrol. 2017. PMID: 27335120 Free PMC article.
92 results