Wynn RF - Search Results

1

Myeloid/Microglial driven autologous hematopoietic stem cell gene therapy corrects a neuronopathic lysosomal disease.

Sergijenko A, Langford-Smith A, Liao AY, Pickford CE, McDermott J, Nowinski G, Langford-Smith KJ, Merry CL, Jones SA, Wraith JE, Wynn RF, Wilkinson FL, Bigger BW. Sergijenko A, et al. Among authors: wynn rf. Mol Ther. 2013 Oct;21(10):1938-49. doi: 10.1038/mt.2013.141. Epub 2013 Jun 7. Mol Ther. 2013. PMID: 23748415 Free PMC article.

2

Donor bone marrow from a sibling with inborn error of metabolism for treatment of acute leukaemia - clinical and biochemical consequences in the non-affected recipient.

Meyer S, Thornley M, Wynn RF, Brennan BM, Carr T, Wraith JE, Will AM. Meyer S, et al. Among authors: wynn rf. Bone Marrow Transplant. 2000 Apr;25(8):909-11. doi: 10.1038/sj.bmt.1702333. Bone Marrow Transplant. 2000. PMID: 10808215

3

Marrow stromal cells from patients affected by MPS I differentially support haematopoietic progenitor cell development.

Baxter MA, Wynn RF, Schyma L, Holmes DK, Wraith JE, Fairbairn LJ, Bellantuono I. Baxter MA, et al. Among authors: wynn rf. J Inherit Metab Dis. 2005;28(6):1045-53. doi: 10.1007/s10545-005-0136-4. J Inherit Metab Dis. 2005. PMID: 16435198

4

Haematopoietic cell transplantation (HCT) in combination with enzyme replacement therapy (ERT) in patients with Hurler syndrome.

Cox-Brinkman J, Boelens JJ, Wraith JE, O'meara A, Veys P, Wijburg FA, Wulffraat N, Wynn RF. Cox-Brinkman J, et al. Among authors: wynn rf. Bone Marrow Transplant. 2006 Jul;38(1):17-21. doi: 10.1038/sj.bmt.1705401. Epub 2006 May 22. Bone Marrow Transplant. 2006. PMID: 16715104 Clinical Trial.

5

Outcomes of hematopoietic stem cell transplantation for Hurler's syndrome in Europe: a risk factor analysis for graft failure.

Boelens JJ, Wynn RF, O'Meara A, Veys P, Bertrand Y, Souillet G, Wraith JE, Fischer A, Cavazzana-Calvo M, Sykora KW, Sedlacek P, Rovelli A, Uiterwaal CS, Wulffraat N. Boelens JJ, et al. Among authors: wynn rf. Bone Marrow Transplant. 2007 Aug;40(3):225-33. doi: 10.1038/sj.bmt.1705718. Epub 2007 May 28. Bone Marrow Transplant. 2007. PMID: 17529997 Free PMC article.

6

Use of enzyme replacement therapy (Laronidase) before hematopoietic stem cell transplantation for mucopolysaccharidosis I: experience in 18 patients.

Wynn RF, Mercer J, Page J, Carr TF, Jones S, Wraith JE. Wynn RF, et al. J Pediatr. 2009 Jan;154(1):135-9. doi: 10.1016/j.jpeds.2008.07.004. J Pediatr. 2009. PMID: 19187736

7

Improved metabolic correction in patients with lysosomal storage disease treated with hematopoietic stem cell transplant compared with enzyme replacement therapy.

Wynn RF, Wraith JE, Mercer J, O'Meara A, Tylee K, Thornley M, Church HJ, Bigger BW. Wynn RF, et al. J Pediatr. 2009 Apr;154(4):609-11. doi: 10.1016/j.jpeds.2008.11.005. J Pediatr. 2009. PMID: 19324223 Clinical Trial.

8

Genistein reduces lysosomal storage in peripheral tissues of mucopolysaccharide IIIB mice.

Malinowska M, Wilkinson FL, Bennett W, Langford-Smith KJ, O'Leary HA, Jakobkiewicz-Banecka J, Wynn R, Wraith JE, Wegrzyn G, Bigger BW. Malinowska M, et al. Mol Genet Metab. 2009 Nov;98(3):235-42. doi: 10.1016/j.ymgme.2009.06.013. Epub 2009 Jun 27. Mol Genet Metab. 2009. PMID: 19632871

9

Evaluation of heparin cofactor II-thrombin complex as a biomarker on blood spots from mucopolysaccharidosis I, IIIA and IIIB mice.

Langford-Smith K, Arasaradnam M, Wraith JE, Wynn R, Bigger BW. Langford-Smith K, et al. Mol Genet Metab. 2010 Mar;99(3):269-74. doi: 10.1016/j.ymgme.2009.10.175. Epub 2009 Oct 23. Mol Genet Metab. 2010. PMID: 19926322

10

Circadian rhythm and suprachiasmatic nucleus alterations in the mouse model of mucopolysaccharidosis IIIB.

Canal MM, Wilkinson FL, Cooper JD, Wraith JE, Wynn R, Bigger BW. Canal MM, et al. Behav Brain Res. 2010 Jun 19;209(2):212-20. doi: 10.1016/j.bbr.2010.01.045. Epub 2010 Feb 4. Behav Brain Res. 2010. PMID: 20138090

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