Wilkinson FL - Search Results

1

Myeloid/Microglial driven autologous hematopoietic stem cell gene therapy corrects a neuronopathic lysosomal disease.

Sergijenko A, Langford-Smith A, Liao AY, Pickford CE, McDermott J, Nowinski G, Langford-Smith KJ, Merry CL, Jones SA, Wraith JE, Wynn RF, Wilkinson FL, Bigger BW. Sergijenko A, et al. Among authors: wilkinson fl. Mol Ther. 2013 Oct;21(10):1938-49. doi: 10.1038/mt.2013.141. Epub 2013 Jun 7. Mol Ther. 2013. PMID: 23748415 Free PMC article.

2

Hematopoietic stem cell and gene therapy corrects primary neuropathology and behavior in mucopolysaccharidosis IIIA mice.

Langford-Smith A, Wilkinson FL, Langford-Smith KJ, Holley RJ, Sergijenko A, Howe SJ, Bennett WR, Jones SA, Wraith J, Merry CL, Wynn RF, Bigger BW. Langford-Smith A, et al. Among authors: wilkinson fl. Mol Ther. 2012 Aug;20(8):1610-21. doi: 10.1038/mt.2012.82. Epub 2012 May 1. Mol Ther. 2012. PMID: 22547151 Free PMC article.

3

Busulfan conditioning enhances engraftment of hematopoietic donor-derived cells in the brain compared with irradiation.

Wilkinson FL, Sergijenko A, Langford-Smith KJ, Malinowska M, Wynn RF, Bigger BW. Wilkinson FL, et al. Mol Ther. 2013 Apr;21(4):868-76. doi: 10.1038/mt.2013.29. Epub 2013 Feb 19. Mol Ther. 2013. PMID: 23423338 Free PMC article.

4

Heparan sulfate inhibits hematopoietic stem and progenitor cell migration and engraftment in mucopolysaccharidosis I.

Watson HA, Holley RJ, Langford-Smith KJ, Wilkinson FL, van Kuppevelt TH, Wynn RF, Wraith JE, Merry CL, Bigger BW. Watson HA, et al. Among authors: wilkinson fl. J Biol Chem. 2014 Dec 26;289(52):36194-203. doi: 10.1074/jbc.M114.599944. Epub 2014 Oct 30. J Biol Chem. 2014. PMID: 25359774 Free PMC article.

5

Hyperactive behaviour in the mouse model of mucopolysaccharidosis IIIB in the open field and home cage environments.

Langford-Smith A, Malinowska M, Langford-Smith KJ, Wegrzyn G, Jones S, Wynn R, Wraith JE, Wilkinson FL, Bigger BW. Langford-Smith A, et al. Among authors: wilkinson fl. Genes Brain Behav. 2011 Aug;10(6):673-82. doi: 10.1111/j.1601-183X.2011.00706.x. Epub 2011 Jun 29. Genes Brain Behav. 2011. PMID: 21635693 Free article.

6

Genistein reduces lysosomal storage in peripheral tissues of mucopolysaccharide IIIB mice.

Malinowska M, Wilkinson FL, Bennett W, Langford-Smith KJ, O'Leary HA, Jakobkiewicz-Banecka J, Wynn R, Wraith JE, Wegrzyn G, Bigger BW. Malinowska M, et al. Among authors: wilkinson fl. Mol Genet Metab. 2009 Nov;98(3):235-42. doi: 10.1016/j.ymgme.2009.06.013. Epub 2009 Jun 27. Mol Genet Metab. 2009. PMID: 19632871

7

Genistein improves neuropathology and corrects behaviour in a mouse model of neurodegenerative metabolic disease.

Malinowska M, Wilkinson FL, Langford-Smith KJ, Langford-Smith A, Brown JR, Crawford BE, Vanier MT, Grynkiewicz G, Wynn RF, Wraith JE, Wegrzyn G, Bigger BW. Malinowska M, et al. Among authors: wilkinson fl. PLoS One. 2010 Dec 1;5(12):e14192. doi: 10.1371/journal.pone.0014192. PLoS One. 2010. PMID: 21152017 Free PMC article.

8

Female mucopolysaccharidosis IIIA mice exhibit hyperactivity and a reduced sense of danger in the open field test.

Langford-Smith A, Langford-Smith KJ, Jones SA, Wynn RF, Wraith JE, Wilkinson FL, Bigger BW. Langford-Smith A, et al. Among authors: wilkinson fl. PLoS One. 2011;6(10):e25717. doi: 10.1371/journal.pone.0025717. Epub 2011 Oct 18. PLoS One. 2011. PMID: 22028789 Free PMC article.

9

Neuropathology in mouse models of mucopolysaccharidosis type I, IIIA and IIIB.

Wilkinson FL, Holley RJ, Langford-Smith KJ, Badrinath S, Liao A, Langford-Smith A, Cooper JD, Jones SA, Wraith JE, Wynn RF, Merry CL, Bigger BW. Wilkinson FL, et al. PLoS One. 2012;7(4):e35787. doi: 10.1371/journal.pone.0035787. Epub 2012 Apr 27. PLoS One. 2012. PMID: 22558223 Free PMC article.

10

Signal one and two blockade are both critical for non-myeloablative murine HSCT across a major histocompatibility complex barrier.

Langford-Smith KJ, Sandiford Z, Langford-Smith A, Wilkinson FL, Jones SA, Wraith JE, Wynn RF, Bigger BW. Langford-Smith KJ, et al. Among authors: wilkinson fl. PLoS One. 2013 Oct 17;8(10):e77632. doi: 10.1371/journal.pone.0077632. eCollection 2013. PLoS One. 2013. PMID: 24147041 Free PMC article.

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