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Page 1
Synthesis of stereochemically and skeletally diverse fused ring systems from functionalized C-glycosides.
Gerard B, Lee MD 4th, Dandapani S, Duvall JR, Fitzgerald ME, Kesavan S, Lowe JT, Marié JC, Pandya BA, Suh BC, O'Shea MW, Dombrowski M, Hamann D, Lemercier B, Murillo T, Akella LB, Foley MA, Marcaurelle LA. Gerard B, et al. Among authors: lowe jt. J Org Chem. 2013 Jun 7;78(11):5160-71. doi: 10.1021/jo4000916. Epub 2013 May 21. J Org Chem. 2013. PMID: 23692141 Free PMC article.
An aldol-based build/couple/pair strategy for the synthesis of medium- and large-sized rings: discovery of macrocyclic histone deacetylase inhibitors.
Marcaurelle LA, Comer E, Dandapani S, Duvall JR, Gerard B, Kesavan S, Lee MD 4th, Liu H, Lowe JT, Marie JC, Mulrooney CA, Pandya BA, Rowley A, Ryba TD, Suh BC, Wei J, Young DW, Akella LB, Ross NT, Zhang YL, Fass DM, Reis SA, Zhao WN, Haggarty SJ, Palmer M, Foley MA. Marcaurelle LA, et al. Among authors: lowe jt. J Am Chem Soc. 2010 Dec 1;132(47):16962-76. doi: 10.1021/ja105119r. Epub 2010 Nov 10. J Am Chem Soc. 2010. PMID: 21067169 Free PMC article.
Synthesis and profiling of a diverse collection of azetidine-based scaffolds for the development of CNS-focused lead-like libraries.
Lowe JT, Lee MD 4th, Akella LB, Davoine E, Donckele EJ, Durak L, Duvall JR, Gerard B, Holson EB, Joliton A, Kesavan S, Lemercier BC, Liu H, Marié JC, Mulrooney CA, Muncipinto G, Welzel-O'Shea M, Panko LM, Rowley A, Suh BC, Thomas M, Wagner FF, Wei J, Foley MA, Marcaurelle LA. Lowe JT, et al. J Org Chem. 2012 Sep 7;77(17):7187-211. doi: 10.1021/jo300974j. Epub 2012 Aug 10. J Org Chem. 2012. PMID: 22853001 Free PMC article.
Total synthesis of 6-deoxypladienolide D and Assessment of Splicing Inhibitory Activity in a Mutant SF3B1 cancer cell line.
Arai K, Buonamici S, Chan B, Corson L, Endo A, Gerard B, Hao MH, Karr C, Kira K, Lee L, Liu X, Lowe JT, Luo T, Marcaurelle LA, Mizui Y, Nevalainen M, O'Shea MW, Park ES, Perino SA, Prajapati S, Shan M, Smith PG, Tivitmahaisoon P, Wang JY, Warmuth M, Wu KM, Yu L, Zhang H, Zheng GZ, Keaney GF. Arai K, et al. Among authors: lowe jt. Org Lett. 2014 Nov 7;16(21):5560-3. doi: 10.1021/ol502556c. Epub 2014 Oct 26. Org Lett. 2014. PMID: 25376106
Total synthesis of bistramide A.
Lowe JT, Wrona IE, Panek JS. Lowe JT, et al. Org Lett. 2007 Jan 18;9(2):327-30. doi: 10.1021/ol062957y. Org Lett. 2007. PMID: 17217296
36 results