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RTP801 is required for ceramide-induced cell-specific death in the murine lung.
Kamocki K, Van Demark M, Fisher A, Rush NI, Presson RG Jr, Hubbard W, Berdyshev EV, Adamsky S, Feinstein E, Gandjeva A, Tuder RM, Petrache I. Kamocki K, et al. Am J Respir Cell Mol Biol. 2013 Jan;48(1):87-93. doi: 10.1165/rcmb.2012-0254OC. Epub 2012 Sep 28. Am J Respir Cell Mol Biol. 2013. PMID: 23024063 Free PMC article.
Apoptotic sphingolipid signaling by ceramides in lung endothelial cells.
Medler TR, Petrusca DN, Lee PJ, Hubbard WC, Berdyshev EV, Skirball J, Kamocki K, Schuchman E, Tuder RM, Petrache I. Medler TR, et al. Among authors: hubbard wc. Am J Respir Cell Mol Biol. 2008 Jun;38(6):639-46. doi: 10.1165/rcmb.2007-0274OC. Epub 2008 Jan 10. Am J Respir Cell Mol Biol. 2008. PMID: 18192502 Free PMC article.
Superoxide dismutase protects against apoptosis and alveolar enlargement induced by ceramide.
Petrache I, Medler TR, Richter AT, Kamocki K, Chukwueke U, Zhen L, Gu Y, Adamowicz J, Schweitzer KS, Hubbard WC, Berdyshev EV, Lungarella G, Tuder RM. Petrache I, et al. Among authors: hubbard wc. Am J Physiol Lung Cell Mol Physiol. 2008 Jul;295(1):L44-53. doi: 10.1152/ajplung.00448.2007. Epub 2008 Apr 25. Am J Physiol Lung Cell Mol Physiol. 2008. PMID: 18441093 Free PMC article.
Lung endothelial monocyte-activating protein 2 is a mediator of cigarette smoke-induced emphysema in mice.
Clauss M, Voswinckel R, Rajashekhar G, Sigua NL, Fehrenbach H, Rush NI, Schweitzer KS, Yildirim AÖ, Kamocki K, Fisher AJ, Gu Y, Safadi B, Nikam S, Hubbard WC, Tuder RM, Twigg HL 3rd, Presson RG, Sethi S, Petrache I. Clauss M, et al. Among authors: hubbard wc. J Clin Invest. 2011 Jun;121(6):2470-9. doi: 10.1172/JCI43881. Epub 2011 May 16. J Clin Invest. 2011. PMID: 21576822 Free PMC article.
Mechanisms of lung endothelial barrier disruption induced by cigarette smoke: role of oxidative stress and ceramides.
Schweitzer KS, Hatoum H, Brown MB, Gupta M, Justice MJ, Beteck B, Van Demark M, Gu Y, Presson RG Jr, Hubbard WC, Petrache I. Schweitzer KS, et al. Among authors: hubbard wc. Am J Physiol Lung Cell Mol Physiol. 2011 Dec;301(6):L836-46. doi: 10.1152/ajplung.00385.2010. Epub 2011 Aug 26. Am J Physiol Lung Cell Mol Physiol. 2011. PMID: 21873444 Free PMC article.
Dihydroceramide-based response to hypoxia.
Devlin CM, Lahm T, Hubbard WC, Van Demark M, Wang KC, Wu X, Bielawska A, Obeid LM, Ivan M, Petrache I. Devlin CM, et al. Among authors: hubbard wc. J Biol Chem. 2011 Nov 4;286(44):38069-38078. doi: 10.1074/jbc.M111.297994. Epub 2011 Sep 13. J Biol Chem. 2011. PMID: 21914808 Free PMC article.
Endothelial disruptive proinflammatory effects of nicotine and e-cigarette vapor exposures.
Schweitzer KS, Chen SX, Law S, Van Demark M, Poirier C, Justice MJ, Hubbard WC, Kim ES, Lai X, Wang M, Kranz WD, Carroll CJ, Ray BD, Bittman R, Goodpaster J, Petrache I. Schweitzer KS, et al. Among authors: hubbard wc. Am J Physiol Lung Cell Mol Physiol. 2015 Jul 15;309(2):L175-87. doi: 10.1152/ajplung.00411.2014. Epub 2015 May 15. Am J Physiol Lung Cell Mol Physiol. 2015. PMID: 25979079 Free PMC article.
161 results