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The anti-proliferative effect of 2-[piperidinoethoxyphenyl]-3-[4-hydroxyphenyl]-2H-benzo(b) pyran is potentiated via induction of estrogen receptor beta and p21 in human endometrial adenocarcinoma cells.
Fatima I, Saxena R, Kharkwal G, Hussain MK, Yadav N, Hajela K, Sankhwar PL, Dwivedi A. Fatima I, et al. Among authors: sankhwar pl. J Steroid Biochem Mol Biol. 2013 Nov;138:123-31. doi: 10.1016/j.jsbmb.2013.04.005. Epub 2013 May 18. J Steroid Biochem Mol Biol. 2013. PMID: 23688837
2,3-Diaryl-2H-1-benzopyran derivatives interfere with classical and non-classical estrogen receptor signaling pathways, inhibit Akt activation and induce apoptosis in human endometrial cancer cells.
Fatima I, Chandra V, Saxena R, Manohar M, Sanghani Y, Hajela K, Negi MP, Sankhwar PL, Jain SK, Dwivedi A. Fatima I, et al. Among authors: sankhwar pl. Mol Cell Endocrinol. 2012 Jan 2;348(1):198-210. doi: 10.1016/j.mce.2011.08.018. Epub 2011 Aug 22. Mol Cell Endocrinol. 2012. PMID: 21878365
Inhibitory effect of 2-(piperidinoethoxyphenyl)-3-(4-hydroxyphenyl)-2H-benzo(b)pyran (K-1) on human primary endometrial hyperplasial cells mediated via combined suppression of Wnt/β-catenin signaling and PI3K/Akt survival pathway.
Chandra V, Fatima I, Manohar M, Popli P, Sirohi VK, Hussain MK, Hajela K, Sankhwar P, Dwivedi A. Chandra V, et al. Cell Death Dis. 2014 Aug 21;5(8):e1380. doi: 10.1038/cddis.2014.334. Cell Death Dis. 2014. PMID: 25144715 Free PMC article.
43 results