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Divergent functions of the Rho GTPases Rac1 and Cdc42 in podocyte injury.
Blattner SM, Hodgin JB, Nishio M, Wylie SA, Saha J, Soofi AA, Vining C, Randolph A, Herbach N, Wanke R, Atkins KB, Gyung Kang H, Henger A, Brakebusch C, Holzman LB, Kretzler M. Blattner SM, et al. Among authors: brakebusch c. Kidney Int. 2013 Nov;84(5):920-30. doi: 10.1038/ki.2013.175. Epub 2013 May 15. Kidney Int. 2013. PMID: 23677246 Free PMC article.
Podocyte-specific loss of Cdc42 leads to congenital nephropathy.
Scott RP, Hawley SP, Ruston J, Du J, Brakebusch C, Jones N, Pawson T. Scott RP, et al. Among authors: brakebusch c. J Am Soc Nephrol. 2012 Jul;23(7):1149-54. doi: 10.1681/ASN.2011121206. Epub 2012 Apr 19. J Am Soc Nephrol. 2012. PMID: 22518006 Free PMC article.
Cdc42 promotes host defenses against fatal infection.
Lee K, Boyd KL, Parekh DV, Kehl-Fie TE, Baldwin HS, Brakebusch C, Skaar EP, Boothby M, Zent R. Lee K, et al. Among authors: brakebusch c. Infect Immun. 2013 Aug;81(8):2714-23. doi: 10.1128/IAI.01114-12. Epub 2013 May 20. Infect Immun. 2013. PMID: 23690402 Free PMC article.
Rho GTPases and cancer.
Li H, Peyrollier K, Kilic G, Brakebusch C. Li H, et al. Among authors: brakebusch c. Biofactors. 2014 Mar-Apr;40(2):226-35. doi: 10.1002/biof.1155. Epub 2013 Dec 21. Biofactors. 2014. PMID: 24375503 Review.
Rho GTPases in cancer: friend or foe?
Svensmark JH, Brakebusch C. Svensmark JH, et al. Among authors: brakebusch c. Oncogene. 2019 Dec;38(50):7447-7456. doi: 10.1038/s41388-019-0963-7. Epub 2019 Aug 19. Oncogene. 2019. PMID: 31427738 Review.
RhoA/Cdc42 signaling drives cytoplasmic maturation but not endomitosis in megakaryocytes.
Heib T, Hermanns HM, Manukjan G, Englert M, Kusch C, Becker IC, Gerber A, Wackerbarth LM, Burkard P, Dandekar T, Balkenhol J, Jahn D, Beck S, Meub M, Dütting S, Stigloher C, Sauer M, Cherpokova D, Schulze H, Brakebusch C, Nieswandt B, Nagy Z, Pleines I. Heib T, et al. Among authors: brakebusch c. Cell Rep. 2021 May 11;35(6):109102. doi: 10.1016/j.celrep.2021.109102. Cell Rep. 2021. PMID: 33979620 Free article.
Rac1 promotes kidney collecting duct integrity by limiting actomyosin activity.
Bock F, Elias BC, Dong X, Parekh DV, Mernaugh G, Viquez OM, Hassan A, Amara VR, Liu J, Brown KL, Terker AS, Chiusa M, Gewin LS, Fogo AB, Brakebusch CH, Pozzi A, Zent R. Bock F, et al. Among authors: brakebusch ch. J Cell Biol. 2021 Nov 1;220(11):e202103080. doi: 10.1083/jcb.202103080. Epub 2021 Oct 14. J Cell Biol. 2021. PMID: 34647970 Free PMC article.
190 results