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PARP is activated in human asthma and its inhibition by olaparib blocks house dust mite-induced disease in mice.
Ghonim MA, Pyakurel K, Ibba SV, Wang J, Rodriguez P, Al-Khami AA, Lammi MR, Kim H, Zea AH, Davis C, Okpechi S, Wyczechowska D, Al-Ghareeb K, Mansy MS, Ochoa A, Naura AS, Boulares AH. Ghonim MA, et al. Among authors: zea ah. Clin Sci (Lond). 2015 Dec;129(11):951-62. doi: 10.1042/CS20150122. Epub 2015 Jul 23. Clin Sci (Lond). 2015. PMID: 26205779 Free PMC article.
Inhibition of indoleamine 2,3-dioxygenase activity by levo-1-methyl tryptophan blocks gamma interferon-induced Chlamydia trachomatis persistence in human epithelial cells.
Ibana JA, Belland RJ, Zea AH, Schust DJ, Nagamatsu T, AbdelRahman YM, Tate DJ, Beatty WL, Aiyar AA, Quayle AJ. Ibana JA, et al. Among authors: zea ah. Infect Immun. 2011 Nov;79(11):4425-37. doi: 10.1128/IAI.05659-11. Epub 2011 Sep 12. Infect Immun. 2011. PMID: 21911470 Free PMC article.
60 results