Brieaddy LE - Search Results

1

Discovery of N-{4-[(3-hydroxyphenyl)-3-methylpiperazin-1-yl]methyl-2-methylpropyl}-4-phenoxybenzamide analogues as selective kappa opioid receptor antagonists.

Kormos CM, Jin C, Cueva JP, Runyon SP, Thomas JB, Brieaddy LE, Mascarella SW, Navarro HA, Gilmour BP, Carroll FI. Kormos CM, et al. Among authors: brieaddy le. J Med Chem. 2013 Jun 13;56(11):4551-67. doi: 10.1021/jm400275h. Epub 2013 May 16. J Med Chem. 2013. PMID: 23651437 Free PMC article.

2

Hydrolytic instability of the important orexin 1 receptor antagonist SB-334867: possible confounding effects on in vivo and in vitro studies.

McElhinny CJ Jr, Lewin AH, Mascarella SW, Runyon S, Brieaddy L, Carroll FI. McElhinny CJ Jr, et al. Bioorg Med Chem Lett. 2012 Nov 1;22(21):6661-4. doi: 10.1016/j.bmcl.2012.08.109. Epub 2012 Sep 7. Bioorg Med Chem Lett. 2012. PMID: 23031594

3

Synthesis and in vitro opioid receptor functional antagonism of analogues of the selective kappa opioid receptor antagonist (3R)-7-hydroxy-N-((1S)-1-{[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethyl-1-piperidinyl]methyl}-2-methylpropyl)-1,2,3,4-tetrahydro-3-isoquinolinecarboxamide (JDTic).

Cai TB, Zou Z, Thomas JB, Brieaddy L, Navarro HA, Carroll FI. Cai TB, et al. J Med Chem. 2008 Mar 27;51(6):1849-60. doi: 10.1021/jm701344b. Epub 2008 Feb 29. J Med Chem. 2008. PMID: 18307295

4

Synthesis, nicotinic acetylcholine receptor binding, and antinociceptive properties of 2-exo-2-(2',3'-disubstituted 5'-pyridinyl)-7-azabicyclo[2.2.1]heptanes: epibatidine analogues.

Carroll FI, Lee JR, Navarro HA, Ma W, Brieaddy LE, Abraham P, Damaj MI, Martin BR. Carroll FI, et al. Among authors: brieaddy le. J Med Chem. 2002 Oct 10;45(21):4755-61. doi: 10.1021/jm0202268. J Med Chem. 2002. PMID: 12361403

5

Synthesis, nicotinic acetylcholine receptor binding, and antinociceptive properties of 2'-fluoro-3'-(substituted phenyl)deschloroepibatidine analogues. Novel nicotinic antagonist.

Carroll FI, Ware R, Brieaddy LE, Navarro HA, Damaj MI, Martin BR. Carroll FI, et al. Among authors: brieaddy le. J Med Chem. 2004 Aug 26;47(18):4588-94. doi: 10.1021/jm040078g. J Med Chem. 2004. PMID: 15317468

6

Synthesis, nicotinic acetylcholine receptor binding, and antinociceptive properties of 3'-substituted deschloroepibatidine analogues. Novel nicotinic antagonists.

Carroll FI, Ma W, Yokota Y, Lee JR, Brieaddy LE, Navarro HA, Damaj MI, Martin BR. Carroll FI, et al. Among authors: brieaddy le. J Med Chem. 2005 Feb 24;48(4):1221-8. doi: 10.1021/jm040160b. J Med Chem. 2005. PMID: 15715488

7

Synthesis and pharmacological characterization of exo-2-(2'-chloro-5-pyridinyl)-7-(endo and exo)-aminobicyclo[2.2.1]heptanes as novel epibatidine analogues.

Carroll FI, Brieaddy LE, Navarro HA, Damaj MI, Martin BR. Carroll FI, et al. Among authors: brieaddy le. J Med Chem. 2005 Nov 17;48(23):7491-5. doi: 10.1021/jm058243v. J Med Chem. 2005. PMID: 16279810

8

Synthesis, monoamine transporter binding, properties, and functional monoamine uptake activity of 3beta-[4-methylphenyl and 4-chlorophenyl]-2 beta-[5-(substituted phenyl)thiazol-2-yl]tropanes.

Gong PK, Blough BE, Brieaddy LE, Huang X, Kuhar MJ, Navarro HA, Carroll FI. Gong PK, et al. Among authors: brieaddy le. J Med Chem. 2007 Jul 26;50(15):3686-95. doi: 10.1021/jm0703035. Epub 2007 Jun 30. J Med Chem. 2007. PMID: 17602602

9

Synthesis, nicotinic acetylcholine receptor binding, and pharmacological properties of 3'-(substituted phenyl)deschloroepibatidine analogs.

Ivy Carroll F, Yokota Y, Ma W, Lee JR, Brieaddy LE, Burgess JP, Navarro HA, Damaj MI, Martin BR. Ivy Carroll F, et al. Among authors: brieaddy le. Bioorg Med Chem. 2008 Jan 15;16(2):746-54. doi: 10.1016/j.bmc.2007.10.027. Epub 2007 Oct 13. Bioorg Med Chem. 2008. PMID: 17964169 Free PMC article.

10

Synthesis and nicotinic acetylcholine receptor binding properties of bridged and fused ring analogues of epibatidine.

Carroll FI, Robinson TP, Brieaddy LE, Atkinson RN, Mascarella SW, Damaj MI, Martin BR, Navarro HA. Carroll FI, et al. Among authors: brieaddy le. J Med Chem. 2007 Dec 13;50(25):6383-91. doi: 10.1021/jm0704696. Epub 2007 Nov 10. J Med Chem. 2007. PMID: 17994682

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

22 results

Search Page

Filters