Lewi PJ - Search Results

1

Diaryltriazine non-nucleoside reverse transcriptase inhibitors are potent candidates for pre-exposure prophylaxis in the prevention of sexual HIV transmission.

Ariën KK, Venkatraj M, Michiels J, Joossens J, Vereecken K, Van der Veken P, Abdellati S, Cuylaerts V, Crucitti T, Heyndrickx L, Heeres J, Augustyns K, Lewi PJ, Vanham G. Ariën KK, et al. Among authors: lewi pj. J Antimicrob Chemother. 2013 Sep;68(9):2038-47. doi: 10.1093/jac/dkt166. Epub 2013 May 3. J Antimicrob Chemother. 2013. PMID: 23645585

2

In vitro evaluation of nonnucleoside reverse transcriptase inhibitors UC-781 and TMC120-R147681 as human immunodeficiency virus microbicides.

Van Herrewege Y, Michiels J, Van Roey J, Fransen K, Kestens L, Balzarini J, Lewi P, Vanham G, Janssen P. Van Herrewege Y, et al. Antimicrob Agents Chemother. 2004 Jan;48(1):337-9. doi: 10.1128/AAC.48.1.337-339.2004. Antimicrob Agents Chemother. 2004. PMID: 14693562 Free PMC article.

3

A series of diaryltriazines and diarylpyrimidines are highly potent nonnucleoside reverse transcriptase inhibitors with possible applications as microbicides.

Van Herrewege Y, Vanham G, Michiels J, Fransen K, Kestens L, Andries K, Janssen P, Lewi P. Van Herrewege Y, et al. Antimicrob Agents Chemother. 2004 Oct;48(10):3684-9. doi: 10.1128/AAC.48.10.3684-3689.2004. Antimicrob Agents Chemother. 2004. PMID: 15388420 Free PMC article.

4

Reverse transcriptase inhibitors as microbicides.

Lewi P, Heeres J, Ariën K, Venkatraj M, Joossens J, Van der Veken P, Augustyns K, Vanham G. Lewi P, et al. Curr HIV Res. 2012 Jan 1;10(1):27-35. doi: 10.2174/157016212799304643. Curr HIV Res. 2012. PMID: 22264043 Review.

5

2,6-Di(arylamino)-3-fluoropyridine Derivatives as HIV Non-Nucleoside Reverse Transcriptase Inhibitors.

Sergeyev S, Yadav AK, Franck P, Michiels J, Lewi P, Heeres J, Vanham G, Ariën KK, Vande Velde CM, De Winter H, Maes BU. Sergeyev S, et al. J Med Chem. 2016 Mar 10;59(5):1854-68. doi: 10.1021/acs.jmedchem.5b01336. Epub 2016 Feb 8. J Med Chem. 2016. PMID: 26785139

6

In vitro pre- and post-exposure prophylaxis using HIV inhibitors as microbicides against cell-free or cell-associated HIV-1 infection.

Terrazas-Aranda K, Van Herrewege Y, Lewi PJ, Van Roey J, Vanham G. Terrazas-Aranda K, et al. Among authors: lewi pj. Antivir Chem Chemother. 2007;18(3):141-51. doi: 10.1177/095632020701800304. Antivir Chem Chemother. 2007. PMID: 17626598 Free article.

7

Novel diarylpyridinones, diarylpyridazinones and diarylphthalazinones as potential HIV-1 nonnucleoside reverse transcriptase inhibitors (NNRTIs).

Venkatraj M, Ariën KK, Heeres J, Dirié B, Joossens J, Van Goethem S, Van der Veken P, Michiels J, Vande Velde CM, Vanham G, Lewi PJ, Augustyns K. Venkatraj M, et al. Among authors: lewi pj. Bioorg Med Chem. 2011 Oct 15;19(20):5924-34. doi: 10.1016/j.bmc.2011.08.060. Epub 2011 Sep 1. Bioorg Med Chem. 2011. PMID: 21930388

8

Development and in vitro evaluation of a vaginal microbicide gel formulation for UAMC01398, a novel diaryltriazine NNRTI against HIV-1.

Grammen C, Ariën KK, Venkatraj M, Joossens J, Van der Veken P, Heeres J, Lewi PJ, Haenen S, Augustyns K, Vanham G, Augustijns P, Brouwers J. Grammen C, et al. Among authors: lewi pj. Antiviral Res. 2014 Jan;101:113-21. doi: 10.1016/j.antiviral.2013.11.005. Epub 2013 Nov 20. Antiviral Res. 2014. PMID: 24269474

9

From human immunodeficiency virus non-nucleoside reverse transcriptase inhibitors to potent and selective antitrypanosomal compounds.

Venkatraj M, Ariën KK, Heeres J, Joossens J, Dirié B, Lyssens S, Michiels J, Cos P, Lewi PJ, Vanham G, Maes L, Van der Veken P, Augustyns K. Venkatraj M, et al. Among authors: lewi pj. Bioorg Med Chem. 2014 Oct 1;22(19):5241-8. doi: 10.1016/j.bmc.2014.08.005. Epub 2014 Aug 14. Bioorg Med Chem. 2014. PMID: 25199582

10

A dual chamber model of female cervical mucosa for the study of HIV transmission and for the evaluation of candidate HIV microbicides.

Van Herrewege Y, Michiels J, Waeytens A, De Boeck G, Salden E, Heyndrickx L, van den Mooter G, de Béthune MP, Andries K, Lewi P, Praet M, Vanham G. Van Herrewege Y, et al. Antiviral Res. 2007 May;74(2):111-24. doi: 10.1016/j.antiviral.2006.10.010. Epub 2006 Nov 7. Antiviral Res. 2007. PMID: 17097156

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