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Farnesoid X receptor activation increases cholesteryl ester transfer protein expression in humans and transgenic mice.
Gautier T, de Haan W, Grober J, Ye D, Bahr MJ, Claudel T, Nijstad N, Van Berkel TJC, Havekes LM, Manns MP, Willems SM, Hogendoorn PCW, Lagrost L, Kuipers F, Van Eck M, Rensen PCN, Tietge UJF. Gautier T, et al. Among authors: claudel t. J Lipid Res. 2013 Aug;54(8):2195-2205. doi: 10.1194/jlr.M038141. Epub 2013 Apr 25. J Lipid Res. 2013. PMID: 23620138 Free PMC article.
The farnesoid X receptor: a novel drug target?
Claudel T, Sturm E, Kuipers F, Staels B. Claudel T, et al. Expert Opin Investig Drugs. 2004 Sep;13(9):1135-48. doi: 10.1517/13543784.13.9.1135. Expert Opin Investig Drugs. 2004. PMID: 15330745 Review.
The Farnesoid X Receptor (FXR) as modulator of bile acid metabolism.
Kuipers F, Claudel T, Sturm E, Staels B. Kuipers F, et al. Among authors: claudel t. Rev Endocr Metab Disord. 2004 Dec;5(4):319-26. doi: 10.1023/B:REMD.0000045103.00467.9a. Rev Endocr Metab Disord. 2004. PMID: 15486464 Review. No abstract available.
High frequency of a retinoid X receptor gamma gene variant in familial combined hyperlipidemia that associates with atherogenic dyslipidemia.
Nohara A, Kawashiri MA, Claudel T, Mizuno M, Tsuchida M, Takata M, Katsuda S, Miwa K, Inazu A, Kuipers F, Kobayashi J, Koizumi J, Yamagishi M, Mabuchi H. Nohara A, et al. Among authors: claudel t. Arterioscler Thromb Vasc Biol. 2007 Apr;27(4):923-8. doi: 10.1161/01.ATV.0000258945.76141.8a. Epub 2007 Feb 1. Arterioscler Thromb Vasc Biol. 2007. PMID: 17272748
Plasma bile acids are not associated with energy metabolism in humans.
Brufau G, Bahr MJ, Staels B, Claudel T, Ockenga J, Böker KH, Murphy EJ, Prado K, Stellaard F, Manns MP, Kuipers F, Tietge UJ. Brufau G, et al. Among authors: claudel t. Nutr Metab (Lond). 2010 Sep 3;7:73. doi: 10.1186/1743-7075-7-73. Nutr Metab (Lond). 2010. PMID: 20815878 Free PMC article.
Farnesoid X receptor represses hepatic human APOA gene expression.
Chennamsetty I, Claudel T, Kostner KM, Baghdasaryan A, Kratky D, Levak-Frank S, Frank S, Gonzalez FJ, Trauner M, Kostner GM. Chennamsetty I, et al. Among authors: claudel t. J Clin Invest. 2011 Sep;121(9):3724-34. doi: 10.1172/JCI45277. Epub 2011 Aug 1. J Clin Invest. 2011. PMID: 21804189 Free PMC article.
Dual farnesoid X receptor/TGR5 agonist INT-767 reduces liver injury in the Mdr2-/- (Abcb4-/-) mouse cholangiopathy model by promoting biliary HCO⁻₃ output.
Baghdasaryan A, Claudel T, Gumhold J, Silbert D, Adorini L, Roda A, Vecchiotti S, Gonzalez FJ, Schoonjans K, Strazzabosco M, Fickert P, Trauner M. Baghdasaryan A, et al. Among authors: claudel t. Hepatology. 2011 Oct;54(4):1303-12. doi: 10.1002/hep.24537. Hepatology. 2011. PMID: 22006858 Free PMC article.
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