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The absence of intrarenal ACE protects against hypertension.
Gonzalez-Villalobos RA, Janjoulia T, Fletcher NK, Giani JF, Nguyen MT, Riquier-Brison AD, Seth DM, Fuchs S, Eladari D, Picard N, Bachmann S, Delpire E, Peti-Peterdi J, Navar LG, Bernstein KE, McDonough AA. Gonzalez-Villalobos RA, et al. Among authors: mcdonough aa. J Clin Invest. 2013 May;123(5):2011-23. doi: 10.1172/JCI65460. Epub 2013 Apr 24. J Clin Invest. 2013. PMID: 23619363 Free PMC article.
AT1A angiotensin receptors in the renal proximal tubule regulate blood pressure.
Gurley SB, Riquier-Brison ADM, Schnermann J, Sparks MA, Allen AM, Haase VH, Snouwaert JN, Le TH, McDonough AA, Koller BH, Coffman TM. Gurley SB, et al. Among authors: mcdonough aa. Cell Metab. 2011 Apr 6;13(4):469-475. doi: 10.1016/j.cmet.2011.03.001. Cell Metab. 2011. PMID: 21459331 Free PMC article.
How does potassium supplementation lower blood pressure?
McDonough AA, Nguyen MT. McDonough AA, et al. Am J Physiol Renal Physiol. 2012 May 1;302(9):F1224-5. doi: 10.1152/ajprenal.00429.2011. Am J Physiol Renal Physiol. 2012. PMID: 22550158 Free PMC article. No abstract available.
Renal angiotensin-converting enzyme is essential for the hypertension induced by nitric oxide synthesis inhibition.
Giani JF, Janjulia T, Kamat N, Seth DM, Blackwell WL, Shah KH, Shen XZ, Fuchs S, Delpire E, Toblli JE, Bernstein KE, McDonough AA, Gonzalez-Villalobos RA. Giani JF, et al. Among authors: mcdonough aa. J Am Soc Nephrol. 2014 Dec;25(12):2752-63. doi: 10.1681/ASN.2013091030. Epub 2014 Jul 10. J Am Soc Nephrol. 2014. PMID: 25012170 Free PMC article.
170 results