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Macheledt JE, Buzdar AU, Hortobagyi GN, Frye DK, Gutterman JU, Holmes FA.Macheledt JE, et al. Among authors: holmes fa.Breast Cancer Res Treat. 1991 Aug;18(3):165-70. doi: 10.1007/BF01990032.Breast Cancer Res Treat. 1991.PMID: 1756259Clinical Trial.