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Studies on the active site of deacetoxycephalosporin C synthase.
Lloyd MD, Lee HJ, Harlos K, Zhang ZH, Baldwin JE, Schofield CJ, Charnock JM, Garner CD, Hara T, Terwisscha van Scheltinga AC, Valegård K, Viklund JA, Hajdu J, Andersson I, Danielsson A, Bhikhabhai R. Lloyd MD, et al. Among authors: zhang zh. J Mol Biol. 1999 Apr 16;287(5):943-60. doi: 10.1006/jmbi.1999.2594. J Mol Biol. 1999. PMID: 10222202 Free article.
Oxygenase-catalyzed ribosome hydroxylation occurs in prokaryotes and humans.
Ge W, Wolf A, Feng T, Ho CH, Sekirnik R, Zayer A, Granatino N, Cockman ME, Loenarz C, Loik ND, Hardy AP, Claridge TDW, Hamed RB, Chowdhury R, Gong L, Robinson CV, Trudgian DC, Jiang M, Mackeen MM, Mccullagh JS, Gordiyenko Y, Thalhammer A, Yamamoto A, Yang M, Liu-Yi P, Zhang Z, Schmidt-Zachmann M, Kessler BM, Ratcliffe PJ, Preston GM, Coleman ML, Schofield CJ. Ge W, et al. Among authors: zhang z. Nat Chem Biol. 2012 Dec;8(12):960-962. doi: 10.1038/nchembio.1093. Epub 2012 Oct 28. Nat Chem Biol. 2012. PMID: 23103944 Free PMC article.
Structural Basis of Prolyl Hydroxylase Domain Inhibition by Molidustat.
Figg WD Jr, McDonough MA, Chowdhury R, Nakashima Y, Zhang Z, Holt-Martyn JP, Krajnc A, Schofield CJ. Figg WD Jr, et al. Among authors: zhang z. ChemMedChem. 2021 Jul 6;16(13):2082-2088. doi: 10.1002/cmdc.202100133. Epub 2021 Apr 9. ChemMedChem. 2021. PMID: 33792169 Free PMC article.
A Small-Molecule Inhibitor of Factor Inhibiting HIF Binding to a Tyrosine-Flip Pocket for the Treatment of Obesity.
Wu Y, Chen Y, Corner TP, Nakashima Y, Salah E, Li Z, Zhang L, Yang L, Tumber A, Sun Z, Wen Y, Zhong A, Yang F, Li X, Zhang Z, Schofield CJ, Zhang X. Wu Y, et al. Among authors: zhang l, zhang z, zhang x. Angew Chem Int Ed Engl. 2024 Oct 1;63(40):e202410438. doi: 10.1002/anie.202410438. Epub 2024 Jul 31. Angew Chem Int Ed Engl. 2024. PMID: 38923188
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