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Genome-wide association study in a Chinese population identifies a susceptibility locus for type 2 diabetes at 7q32 near PAX4.
Ma RC, Hu C, Tam CH, Zhang R, Kwan P, Leung TF, Thomas GN, Go MJ, Hara K, Sim X, Ho JS, Wang C, Li H, Lu L, Wang Y, Li JW, Wang Y, Lam VK, Wang J, Yu W, Kim YJ, Ng DP, Fujita H, Panoutsopoulou K, Day-Williams AG, Lee HM, Ng AC, Fang YJ, Kong AP, Jiang F, Ma X, Hou X, Tang S, Lu J, Yamauchi T, Tsui SK, Woo J, Leung PC, Zhang X, Tang NL, Sy HY, Liu J, Wong TY, Lee JY, Maeda S, Xu G, Cherny SS, Chan TF, Ng MC, Xiang K, Morris AP; DIAGRAM Consortium; Keildson S; MuTHER Consortium; Hu R, Ji L, Lin X, Cho YS, Kadowaki T, Tai ES, Zeggini E, McCarthy MI, Hon KL, Baum L, Tomlinson B, So WY, Bao Y, Chan JC, Jia W. Ma RC, et al. Among authors: mccarthy mi. Diabetologia. 2013 Jun;56(6):1291-305. doi: 10.1007/s00125-013-2874-4. Epub 2013 Mar 27. Diabetologia. 2013. PMID: 23532257 Free PMC article.
Analysis of the contribution to type 2 diabetes susceptibility of sequence variation in the gene encoding stearoyl-CoA desaturase, a key regulator of lipid and carbohydrate metabolism.
Liew CF, Groves CJ, Wiltshire S, Zeggini E, Frayling TM, Owen KR, Walker M, Hitman GA, Levy JC, O'rahilly S, Hattersley AT, Johnston DG, McCarthy MI. Liew CF, et al. Among authors: mccarthy mi. Diabetologia. 2004 Dec;47(12):2168-75. doi: 10.1007/s00125-004-1575-4. Epub 2004 Dec 15. Diabetologia. 2004. PMID: 15662557
TCF7L2: the biggest story in diabetes genetics since HLA?
Zeggini E, McCarthy MI. Zeggini E, et al. Among authors: mccarthy mi. Diabetologia. 2007 Jan;50(1):1-4. doi: 10.1007/s00125-006-0507-x. Diabetologia. 2007. PMID: 17096114 Free PMC article. No abstract available.
An association analysis of the HLA gene region in latent autoimmune diabetes in adults.
Desai M, Zeggini E, Horton VA, Owen KR, Hattersley AT, Levy JC, Walker M, Gillespie KM, Bingley PJ, Hitman GA, Holman RR, McCarthy MI, Clark A. Desai M, et al. Among authors: mccarthy mi. Diabetologia. 2007 Jan;50(1):68-73. doi: 10.1007/s00125-006-0513-z. Epub 2006 Dec 2. Diabetologia. 2007. PMID: 17143607 Free PMC article.
Disparate genetic influences on polycystic ovary syndrome (PCOS) and type 2 diabetes revealed by a lack of association between common variants within the TCF7L2 gene and PCOS.
Barber TM, Bennett AJ, Groves CJ, Sovio U, Ruokonen A, Martikainen H, Pouta A, Hartikainen AL, Elliott P, Wass JA, Järvelin MR, Zeggini E, Franks S, McCarthy MI. Barber TM, et al. Among authors: mccarthy mi. Diabetologia. 2007 Nov;50(11):2318-22. doi: 10.1007/s00125-007-0804-z. Epub 2007 Sep 6. Diabetologia. 2007. PMID: 17805508
786 results