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Downregulation of deoxycytidine kinase in cytarabine-resistant mantle cell lymphoma cells confers cross-resistance to nucleoside analogs gemcitabine, fludarabine and cladribine, but not to other classes of anti-lymphoma agents.
Klanova M, Lorkova L, Vit O, Maswabi B, Molinsky J, Pospisilova J, Vockova P, Mavis C, Lateckova L, Kulvait V, Vejmelkova D, Jaksa R, Hernandez F, Trneny M, Vokurka M, Petrak J, Klener P Jr. Klanova M, et al. Among authors: lorkova l. Mol Cancer. 2014 Jun 27;13:159. doi: 10.1186/1476-4598-13-159. Mol Cancer. 2014. PMID: 24972933 Free PMC article.
Proteomic and transcriptomic analysis of heart failure due to volume overload in a rat aorto-caval fistula model provides support for new potential therapeutic targets - monoamine oxidase A and transglutaminase 2.
Petrak J, Pospisilova J, Sedinova M, Jedelsky P, Lorkova L, Vit O, Kolar M, Strnad H, Benes J, Sedmera D, Cervenka L, Melenovsky V. Petrak J, et al. Among authors: lorkova l. Proteome Sci. 2011 Nov 11;9(1):69. doi: 10.1186/1477-5956-9-69. Proteome Sci. 2011. PMID: 22078724 Free PMC article.
Quinone reductase acts as a redox switch of the 20S yeast proteasome.
Sollner S, Schober M, Wagner A, Prem A, Lorkova L, Palfey BA, Groll M, Macheroux P. Sollner S, et al. Among authors: lorkova l. EMBO Rep. 2009 Jan;10(1):65-70. doi: 10.1038/embor.2008.218. Epub 2008 Nov 21. EMBO Rep. 2009. PMID: 19029946 Free PMC article.