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Attenuation of miR-126 activity expands HSC in vivo without exhaustion.
Lechman ER, Gentner B, van Galen P, Giustacchini A, Saini M, Boccalatte FE, Hiramatsu H, Restuccia U, Bachi A, Voisin V, Bader GD, Dick JE, Naldini L. Lechman ER, et al. Among authors: saini m. Cell Stem Cell. 2012 Dec 7;11(6):799-811. doi: 10.1016/j.stem.2012.09.001. Epub 2012 Nov 8. Cell Stem Cell. 2012. PMID: 23142521 Free PMC article.
Identification of a population of blood circulating tumor cells from breast cancer patients that initiates metastasis in a xenograft assay.
Baccelli I, Schneeweiss A, Riethdorf S, Stenzinger A, Schillert A, Vogel V, Klein C, Saini M, Bäuerle T, Wallwiener M, Holland-Letz T, Höfner T, Sprick M, Scharpff M, Marmé F, Sinn HP, Pantel K, Weichert W, Trumpp A. Baccelli I, et al. Among authors: saini m. Nat Biotechnol. 2013 Jun;31(6):539-44. doi: 10.1038/nbt.2576. Epub 2013 Apr 21. Nat Biotechnol. 2013. PMID: 23609047
The sialyl-glycolipid stage-specific embryonic antigen 4 marks a subpopulation of chemotherapy-resistant breast cancer cells with mesenchymal features.
Aloia A, Petrova E, Tomiuk S, Bissels U, Déas O, Saini M, Zickgraf FM, Wagner S, Spaich S, Sütterlin M, Schneeweiss A, Reitberger M, Rüberg S, Gerstmayer B, Agorku D, Knöbel S, Terranegra A, Falleni M, Soldati L, Sprick MR, Trumpp A, Judde JG, Bosio A, Cairo S, Hardt O. Aloia A, et al. Among authors: saini m. Breast Cancer Res. 2015 Nov 25;17(1):146. doi: 10.1186/s13058-015-0652-6. Breast Cancer Res. 2015. PMID: 26607327 Free PMC article.
Sustained prognostic impact of circulating tumor cell status and kinetics upon further progression of metastatic breast cancer.
Jauch SF, Riethdorf S, Sprick MR, Schütz F, Schönfisch B, Brucker SY, Deutsch TM, Nees J, Saini M, Becker LM, Burwinkel B, Sinn P, Marmé F, Pantel K, Jäger D, Sohn C, Trumpp A, Wallwiener M, Schneeweiss A. Jauch SF, et al. Among authors: saini m. Breast Cancer Res Treat. 2019 Jan;173(1):155-165. doi: 10.1007/s10549-018-4972-y. Epub 2018 Oct 1. Breast Cancer Res Treat. 2019. PMID: 30276763
Single cell polarity in liquid phase facilitates tumour metastasis.
Lorentzen A, Becker PF, Kosla J, Saini M, Weidele K, Ronchi P, Klein C, Wolf MJ, Geist F, Seubert B, Ringelhan M, Mihic-Probst D, Esser K, Roblek M, Kuehne F, Bianco G, O'Connor T, Müller Q, Schuck K, Lange S, Hartmann D, Spaich S, Groß O, Utikal J, Haferkamp S, Sprick MR, Damle-Vartak A, Hapfelmeier A, Hüser N, Protzer U, Trumpp A, Saur D, Vartak N, Klein CA, Polzer B, Borsig L, Heikenwalder M. Lorentzen A, et al. Among authors: saini m. Nat Commun. 2018 Feb 28;9(1):887. doi: 10.1038/s41467-018-03139-6. Nat Commun. 2018. PMID: 29491397 Free PMC article.
Acquired CYP19A1 amplification is an early specific mechanism of aromatase inhibitor resistance in ERα metastatic breast cancer.
Magnani L, Frige G, Gadaleta RM, Corleone G, Fabris S, Kempe MH, Verschure PJ, Barozzi I, Vircillo V, Hong SP, Perone Y, Saini M, Trumpp A, Viale G, Neri A, Ali S, Colleoni MA, Pruneri G, Minucci S. Magnani L, et al. Among authors: saini m. Nat Genet. 2017 Mar;49(3):444-450. doi: 10.1038/ng.3773. Epub 2017 Jan 23. Nat Genet. 2017. PMID: 28112739 Free PMC article.
The metastatic spread of breast cancer accelerates during sleep.
Diamantopoulou Z, Castro-Giner F, Schwab FD, Foerster C, Saini M, Budinjas S, Strittmatter K, Krol I, Seifert B, Heinzelmann-Schwarz V, Kurzeder C, Rochlitz C, Vetter M, Weber WP, Aceto N. Diamantopoulou Z, et al. Among authors: saini m. Nature. 2022 Jul;607(7917):156-162. doi: 10.1038/s41586-022-04875-y. Epub 2022 Jun 22. Nature. 2022. PMID: 35732738
685 results