Kiernan A - Search Results

1

Sox2 cooperates with inflammation-mediated Stat3 activation in the malignant transformation of foregut basal progenitor cells.

Liu K, Jiang M, Lu Y, Chen H, Sun J, Wu S, Ku WY, Nakagawa H, Kita Y, Natsugoe S, Peters JH, Rustgi A, Onaitis MW, Kiernan A, Chen X, Que J. Liu K, et al. Among authors: kiernan a. Cell Stem Cell. 2013 Mar 7;12(3):304-15. doi: 10.1016/j.stem.2013.01.007. Cell Stem Cell. 2013. PMID: 23472872 Free PMC article.

2

Ectopic expression of activated notch or SOX2 reveals similar and unique roles in the development of the sensory cell progenitors in the mammalian inner ear.

Pan W, Jin Y, Chen J, Rottier RJ, Steel KP, Kiernan AE. Pan W, et al. J Neurosci. 2013 Oct 9;33(41):16146-57. doi: 10.1523/JNEUROSCI.3150-12.2013. J Neurosci. 2013. PMID: 24107947 Free PMC article.

3

Activated notch causes deafness by promoting a supporting cell phenotype in developing auditory hair cells.

Savoy-Burke G, Gilels FA, Pan W, Pratt D, Que J, Gan L, White PM, Kiernan AE. Savoy-Burke G, et al. Among authors: kiernan ae. PLoS One. 2014 Sep 29;9(9):e108160. doi: 10.1371/journal.pone.0108160. eCollection 2014. PLoS One. 2014. PMID: 25264928 Free PMC article.

4

SOX2 is required for inner ear neurogenesis.

Steevens AR, Sookiasian DL, Glatzer JC, Kiernan AE. Steevens AR, et al. Sci Rep. 2017 Jun 22;7(1):4086. doi: 10.1038/s41598-017-04315-2. Sci Rep. 2017. PMID: 28642583 Free PMC article.

5

SOX2 is required for inner ear growth and cochlear nonsensory formation before sensory development.

Steevens AR, Glatzer JC, Kellogg CC, Low WC, Santi PA, Kiernan AE. Steevens AR, et al. Among authors: kiernan ae. Development. 2019 Jun 21;146(13):dev170522. doi: 10.1242/dev.170522. Development. 2019. PMID: 31152002 Free PMC article.

6

Using genetic mouse models to gain insight into glaucoma: Past results and future possibilities.

Fernandes KA, Harder JM, Williams PA, Rausch RL, Kiernan AE, Nair KS, Anderson MG, John SW, Howell GR, Libby RT. Fernandes KA, et al. Among authors: kiernan ae. Exp Eye Res. 2015 Dec;141:42-56. doi: 10.1016/j.exer.2015.06.019. Epub 2015 Jun 24. Exp Eye Res. 2015. PMID: 26116903 Free PMC article. Review.

7

Notch-mediated lateral induction is necessary to maintain vestibular prosensory identity during inner ear development.

Brown RM 2nd, Nelson JC, Zhang H, Kiernan AE, Groves AK. Brown RM 2nd, et al. Dev Biol. 2020 Jun 1;462(1):74-84. doi: 10.1016/j.ydbio.2020.02.015. Epub 2020 Mar 5. Dev Biol. 2020. PMID: 32147304 Free PMC article.

8

Deletion of the Notch ligand Jagged1 during cochlear maturation leads to inner hair cell defects and hearing loss.

Gilels FA, Wang J, Bullen A, White PM, Kiernan AE. Gilels FA, et al. Among authors: kiernan ae. Cell Death Dis. 2022 Nov 18;13(11):971. doi: 10.1038/s41419-022-05380-w. Cell Death Dis. 2022. PMID: 36400760 Free PMC article.

9

Notch signaling during cell fate determination in the inner ear.

Kiernan AE. Kiernan AE. Semin Cell Dev Biol. 2013 May;24(5):470-9. doi: 10.1016/j.semcdb.2013.04.002. Epub 2013 Apr 8. Semin Cell Dev Biol. 2013. PMID: 23578865 Free PMC article. Review.

10

Notch signaling is required for the generation of hair cells and supporting cells in the mammalian inner ear.

Pan W, Jin Y, Stanger B, Kiernan AE. Pan W, et al. Proc Natl Acad Sci U S A. 2010 Sep 7;107(36):15798-803. doi: 10.1073/pnas.1003089107. Epub 2010 Aug 23. Proc Natl Acad Sci U S A. 2010. PMID: 20733081 Free PMC article.

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