Singer T - Search Results

1

Effect of GLP1R agonists taspoglutide and liraglutide on primary thyroid C-cells from rodent and man.

Boess F, Bertinetti-Lapatki C, Zoffmann S, George C, Pfister T, Roth A, Lee SM, Thasler WE, Singer T, Suter L. Boess F, et al. Among authors: singer t. J Mol Endocrinol. 2013 Apr 12;50(3):325-36. doi: 10.1530/JME-12-0186. Print 2013 Jun. J Mol Endocrinol. 2013. PMID: 23463748

2

A long-term three dimensional liver co-culture system for improved prediction of clinically relevant drug-induced hepatotoxicity.

Kostadinova R, Boess F, Applegate D, Suter L, Weiser T, Singer T, Naughton B, Roth A. Kostadinova R, et al. Among authors: singer t. Toxicol Appl Pharmacol. 2013 Apr 1;268(1):1-16. doi: 10.1016/j.taap.2013.01.012. Epub 2013 Jan 23. Toxicol Appl Pharmacol. 2013. PMID: 23352505

3

Use of early phenotypic in vivo markers to assess human relevance of an unusual rodent non-genotoxic carcinogen in vitro.

Boess F, Lenz B, Funk J, Niederhauser U, Bassett S, Zhang JD, Singer T, Roth AB. Boess F, et al. Among authors: singer t. Toxicology. 2017 Mar 15;379:48-61. doi: 10.1016/j.tox.2017.01.018. Epub 2017 Feb 5. Toxicology. 2017. PMID: 28174063

4

The application of 3D cell models to support drug safety assessment: opportunities & challenges.

Roth A, Singer T. Roth A, et al. Among authors: singer t. Adv Drug Deliv Rev. 2014 Apr;69-70:179-89. doi: 10.1016/j.addr.2013.12.005. Epub 2013 Dec 27. Adv Drug Deliv Rev. 2014. PMID: 24378580 Review.

5

Establishment of a Predictive In Vitro Assay for Assessment of the Hepatotoxic Potential of Oligonucleotide Drugs.

Sewing S, Boess F, Moisan A, Bertinetti-Lapatki C, Minz T, Hedtjaern M, Tessier Y, Schuler F, Singer T, Roth AB. Sewing S, et al. Among authors: singer t. PLoS One. 2016 Jul 21;11(7):e0159431. doi: 10.1371/journal.pone.0159431. eCollection 2016. PLoS One. 2016. PMID: 27442522 Free PMC article.

6

A label-free, impedance-based real time assay to identify drug-induced toxicities and differentiate cytostatic from cytotoxic effects.

Kustermann S, Boess F, Buness A, Schmitz M, Watzele M, Weiser T, Singer T, Suter L, Roth A. Kustermann S, et al. Among authors: singer t. Toxicol In Vitro. 2013 Aug;27(5):1589-95. doi: 10.1016/j.tiv.2012.08.019. Epub 2012 Aug 28. Toxicol In Vitro. 2013. PMID: 22954529

7

A real-time impedance-based screening assay for drug-induced vascular leakage.

Kustermann S, Manigold T, Ploix C, Skubatz M, Heckel T, Hinton H, Weiser T, Singer T, Suter L, Roth A. Kustermann S, et al. Among authors: singer t. Toxicol Sci. 2014 Apr;138(2):333-43. doi: 10.1093/toxsci/kft336. Epub 2014 Jan 2. Toxicol Sci. 2014. PMID: 24385420

8

Assessing single-stranded oligonucleotide drug-induced effects in vitro reveals key risk factors for thrombocytopenia.

Sewing S, Roth AB, Winter M, Dieckmann A, Bertinetti-Lapatki C, Tessier Y, McGinnis C, Huber S, Koller E, Ploix C, Reed JC, Singer T, Rothfuss A. Sewing S, et al. Among authors: singer t. PLoS One. 2017 Nov 6;12(11):e0187574. doi: 10.1371/journal.pone.0187574. eCollection 2017. PLoS One. 2017. PMID: 29107969 Free PMC article.

9

A simple whole blood bioassay detects cytokine responses to anti-CD28SA and anti-CD52 antibodies.

Bailey L, Moreno L, Manigold T, Krasniqi S, Kropshofer H, Hinton H, Singer T, Suter L, Hansel TT, Mitchell JA. Bailey L, et al. Among authors: singer t. J Pharmacol Toxicol Methods. 2013 Sep-Oct;68(2):231-239. doi: 10.1016/j.vascn.2012.12.003. Epub 2012 Dec 29. J Pharmacol Toxicol Methods. 2013. PMID: 23280407

10

Toxicogenomics in the pharmaceutical industry: hollow promises or real benefit?

Lühe A, Suter L, Ruepp S, Singer T, Weiser T, Albertini S. Lühe A, et al. Among authors: singer t. Mutat Res. 2005 Aug 4;575(1-2):102-15. doi: 10.1016/j.mrfmmm.2005.02.009. Epub 2005 Apr 25. Mutat Res. 2005. PMID: 15924886 Review.

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