Delgado A - Search Results

1

Acid ceramidase as a therapeutic target in metastatic prostate cancer.

Camacho L, Meca-Cortés O, Abad JL, García S, Rubio N, Díaz A, Celià-Terrassa T, Cingolani F, Bermudo R, Fernández PL, Blanco J, Delgado A, Casas J, Fabriàs G, Thomson TM. Camacho L, et al. Among authors: delgado a. J Lipid Res. 2013 May;54(5):1207-20. doi: 10.1194/jlr.M032375. Epub 2013 Feb 19. J Lipid Res. 2013. PMID: 23423838 Free PMC article.

2

Disclosing new inhibitors by finding similarities in three-dimensional active-site architectures of polynuclear zinc phospholipases and aminopeptidases.

González-Roura A, Navarro I, Delgado A, Llebaria A, Casas J. González-Roura A, et al. Among authors: delgado a. Angew Chem Int Ed Engl. 2004 Feb 6;43(7):862-5. doi: 10.1002/anie.200352241. Angew Chem Int Ed Engl. 2004. PMID: 14767959 No abstract available.

3

New aminocyclitols as modulators of glucosylceramide metabolism.

Egido-Gabás M, Serrano P, Casas J, Llebaria A, Delgado A. Egido-Gabás M, et al. Among authors: delgado a. Org Biomol Chem. 2005 Apr 7;3(7):1195-201. doi: 10.1039/b411473f. Epub 2005 Mar 1. Org Biomol Chem. 2005. PMID: 15785807

4

Design, synthesis and activity as acid ceramidase inhibitors of 2-oxooctanoyl and N-oleoylethanolamine analogues.

Grijalvo S, Bedia C, Triola G, Casas J, Llebaria A, Teixidó J, Rabal O, Levade T, Delgado A, Fabriàs G. Grijalvo S, et al. Among authors: delgado a. Chem Phys Lipids. 2006 Oct;144(1):69-84. doi: 10.1016/j.chemphyslip.2006.07.001. Epub 2006 Aug 7. Chem Phys Lipids. 2006. PMID: 16942762

5

Inhibitors of sphingolipid metabolism enzymes.

Delgado A, Casas J, Llebaria A, Abad JL, Fabrias G. Delgado A, et al. Biochim Biophys Acta. 2006 Dec;1758(12):1957-77. doi: 10.1016/j.bbamem.2006.08.017. Epub 2006 Sep 1. Biochim Biophys Acta. 2006. PMID: 17049336 Free article. Review.

6

Solid-phase synthesis of a combinatorial library of dihydroceramide analogues and its activity in human alveolar epithelial cells.

Villorbina G, Canals D, Carde L, Grijalvo S, Pascual R, Rabal O, Teixidó J, Fabriàs G, Llebaria A, Casas J, Delgado A. Villorbina G, et al. Among authors: delgado a. Bioorg Med Chem. 2007 Jan 1;15(1):50-62. doi: 10.1016/j.bmc.2006.10.024. Epub 2006 Oct 17. Bioorg Med Chem. 2007. PMID: 17081760

7

Combinatorial approach to N-substituted aminocyclitol libraries by solution-phase parallel synthesis and preliminary evaluation as glucocerebrosidase inhibitors.

Serrano P, Casas J, Zucco M, Emeric G, Egido-Gabás M, Llebaria A, Delgado A. Serrano P, et al. Among authors: delgado a. J Comb Chem. 2007 Jan-Feb;9(1):43-52. doi: 10.1021/cc060080o. J Comb Chem. 2007. PMID: 17206831

8

Chemical tools to investigate sphingolipid metabolism and functions.

Delgado A, Casas J, Llebaria A, Abad JL, Fabriás G. Delgado A, et al. ChemMedChem. 2007 May;2(5):580-606. doi: 10.1002/cmdc.200600195. ChemMedChem. 2007. PMID: 17252619 Review.

9

Aminocyclitols as pharmacological chaperones for glucocerebrosidase, a defective enzyme in Gaucher disease.

Egido-Gabás M, Canals D, Casas J, Llebaria A, Delgado A. Egido-Gabás M, et al. Among authors: delgado a. ChemMedChem. 2007 Jul;2(7):992-4. doi: 10.1002/cmdc.200700061. ChemMedChem. 2007. PMID: 17479993 No abstract available.

10

Practical synthesis of (-)-1-amino-1-deoxy-myo-inositol from achiral precursors.

Gonzalez-Bulnes P, Casas J, Delgado A, Llebaria A. Gonzalez-Bulnes P, et al. Among authors: delgado a. Carbohydr Res. 2007 Sep 3;342(12-13):1947-52. doi: 10.1016/j.carres.2007.04.024. Epub 2007 May 5. Carbohydr Res. 2007. PMID: 17524374

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