Pearson CE - Search Results

1

The disease-associated r(GGGGCC)n repeat from the C9orf72 gene forms tract length-dependent uni- and multimolecular RNA G-quadruplex structures.

Reddy K, Zamiri B, Stanley SYR, Macgregor RB Jr, Pearson CE. Reddy K, et al. Among authors: pearson ce. J Biol Chem. 2013 Apr 5;288(14):9860-9866. doi: 10.1074/jbc.C113.452532. Epub 2013 Feb 19. J Biol Chem. 2013. PMID: 23423380 Free PMC article.

2

In vitro (CTG)*(CAG) expansions and deletions by human cell extracts.

Panigrahi GB, Cleary JD, Pearson CE. Panigrahi GB, et al. Among authors: pearson ce. J Biol Chem. 2002 Apr 19;277(16):13926-34. doi: 10.1074/jbc.M109761200. Epub 2002 Feb 6. J Biol Chem. 2002. PMID: 11832482 Free article.

3

Fidelity of primate cell repair of a double-strand break within a (CTG).(CAG) tract. Effect of slipped DNA structures.

Marcadier JL, Pearson CE. Marcadier JL, et al. Among authors: pearson ce. J Biol Chem. 2003 Sep 5;278(36):33848-56. doi: 10.1074/jbc.M304284200. Epub 2003 Jun 14. J Biol Chem. 2003. PMID: 12807901 Free article.

4

The contribution of cis-elements to disease-associated repeat instability: clinical and experimental evidence.

Cleary JD, Pearson CE. Cleary JD, et al. Among authors: pearson ce. Cytogenet Genome Res. 2003;100(1-4):25-55. doi: 10.1159/000072837. Cytogenet Genome Res. 2003. PMID: 14526163 Review.

5

CTG/CAG repeat instability is modulated by the levels of human DNA ligase I and its interaction with proliferating cell nuclear antigen: a distinction between replication and slipped-DNA repair.

López Castel A, Tomkinson AE, Pearson CE. López Castel A, et al. Among authors: pearson ce. J Biol Chem. 2009 Sep 25;284(39):26631-45. doi: 10.1074/jbc.M109.034405. Epub 2009 Jul 22. J Biol Chem. 2009. PMID: 19628465 Free PMC article.

6

Determinants of R-loop formation at convergent bidirectionally transcribed trinucleotide repeats.

Reddy K, Tam M, Bowater RP, Barber M, Tomlinson M, Nichol Edamura K, Wang YH, Pearson CE. Reddy K, et al. Among authors: pearson ce. Nucleic Acids Res. 2011 Mar;39(5):1749-62. doi: 10.1093/nar/gkq935. Epub 2010 Nov 4. Nucleic Acids Res. 2011. PMID: 21051337 Free PMC article.

7

Repeat associated non-ATG translation initiation: one DNA, two transcripts, seven reading frames, potentially nine toxic entities!

Pearson CE. Pearson CE. PLoS Genet. 2011 Mar;7(3):e1002018. doi: 10.1371/journal.pgen.1002018. Epub 2011 Mar 10. PLoS Genet. 2011. PMID: 21423665 Free PMC article. Review.

8

Human mismatch repair protein hMutLα is required to repair short slipped-DNAs of trinucleotide repeats.

Panigrahi GB, Slean MM, Simard JP, Pearson CE. Panigrahi GB, et al. Among authors: pearson ce. J Biol Chem. 2012 Dec 7;287(50):41844-50. doi: 10.1074/jbc.M112.420398. Epub 2012 Oct 18. J Biol Chem. 2012. PMID: 23086927 Free PMC article.

9

Interconverting conformations of slipped-DNA junctions formed by trinucleotide repeats affect repair outcome.

Slean MM, Reddy K, Wu B, Nichol Edamura K, Kekis M, Nelissen FH, Aspers RL, Tessari M, Schärer OD, Wijmenga SS, Pearson CE. Slean MM, et al. Among authors: pearson ce. Biochemistry. 2013 Feb 5;52(5):773-85. doi: 10.1021/bi301369b. Epub 2013 Jan 22. Biochemistry. 2013. PMID: 23339280 Free PMC article.

10

RAN translation: fragile X in the running.

Reddy K, Pearson CE. Reddy K, et al. Among authors: pearson ce. Neuron. 2013 May 8;78(3):405-8. doi: 10.1016/j.neuron.2013.04.034. Neuron. 2013. PMID: 23664607 Free article.

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