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Gab2 phosphorylation by RSK inhibits Shp2 recruitment and cell motility.
Zhang X, Lavoie G, Fort L, Huttlin EL, Tcherkezian J, Galan JA, Gu H, Gygi SP, Carreno S, Roux PP. Zhang X, et al. Among authors: fort l. Mol Cell Biol. 2013 Apr;33(8):1657-70. doi: 10.1128/MCB.01353-12. Epub 2013 Feb 11. Mol Cell Biol. 2013. PMID: 23401857 Free PMC article.
Fam49/CYRI interacts with Rac1 and locally suppresses protrusions.
Fort L, Batista JM, Thomason PA, Spence HJ, Whitelaw JA, Tweedy L, Greaves J, Martin KJ, Anderson KI, Brown P, Lilla S, Neilson MP, Tafelmeyer P, Zanivan S, Ismail S, Bryant DM, Tomkinson NCO, Chamberlain LH, Mastick GS, Insall RH, Machesky LM. Fort L, et al. Nat Cell Biol. 2018 Oct;20(10):1159-1171. doi: 10.1038/s41556-018-0198-9. Epub 2018 Sep 24. Nat Cell Biol. 2018. PMID: 30250061 Free PMC article.
CYRI/ Fam49 Proteins Represent a New Class of Rac1 Interactors.
Whitelaw JA, Lilla S, Paul NR, Fort L, Zanivan S, Machesky LM. Whitelaw JA, et al. Among authors: fort l. Commun Integr Biol. 2019 Jul 23;12(1):112-118. doi: 10.1080/19420889.2019.1643665. eCollection 2019. Commun Integr Biol. 2019. PMID: 31413787 Free PMC article.
N-WASP Control of LPAR1 Trafficking Establishes Response to Self-Generated LPA Gradients to Promote Pancreatic Cancer Cell Metastasis.
Juin A, Spence HJ, Martin KJ, McGhee E, Neilson M, Cutiongco MFA, Gadegaard N, Mackay G, Fort L, Lilla S, Kalna G, Thomason P, Koh YWH, Norman JC, Insall RH, Machesky LM. Juin A, et al. Among authors: fort l. Dev Cell. 2019 Nov 18;51(4):431-445.e7. doi: 10.1016/j.devcel.2019.09.018. Epub 2019 Oct 24. Dev Cell. 2019. PMID: 31668663 Free PMC article.
Mitochondrial permeabilization engages NF-κB-dependent anti-tumour activity under caspase deficiency.
Giampazolias E, Zunino B, Dhayade S, Bock F, Cloix C, Cao K, Roca A, Lopez J, Ichim G, Proïcs E, Rubio-Patiño C, Fort L, Yatim N, Woodham E, Orozco S, Taraborrelli L, Peltzer N, Lecis D, Machesky L, Walczak H, Albert ML, Milling S, Oberst A, Ricci JE, Ryan KM, Blyth K, Tait SWG. Giampazolias E, et al. Among authors: fort l. Nat Cell Biol. 2017 Sep;19(9):1116-1129. doi: 10.1038/ncb3596. Epub 2017 Aug 28. Nat Cell Biol. 2017. PMID: 28846096 Free PMC article.
45 results