Hieter P - Search Results

1

An evolutionarily conserved synthetic lethal interaction network identifies FEN1 as a broad-spectrum target for anticancer therapeutic development.

van Pel DM, Barrett IJ, Shimizu Y, Sajesh BV, Guppy BJ, Pfeifer T, McManus KJ, Hieter P. van Pel DM, et al. Among authors: hieter p. PLoS Genet. 2013;9(1):e1003254. doi: 10.1371/journal.pgen.1003254. Epub 2013 Jan 31. PLoS Genet. 2013. PMID: 23382697 Free PMC article.

2

Specific synthetic lethal killing of RAD54B-deficient human colorectal cancer cells by FEN1 silencing.

McManus KJ, Barrett IJ, Nouhi Y, Hieter P. McManus KJ, et al. Among authors: hieter p. Proc Natl Acad Sci U S A. 2009 Mar 3;106(9):3276-81. doi: 10.1073/pnas.0813414106. Epub 2009 Feb 13. Proc Natl Acad Sci U S A. 2009. PMID: 19218431 Free PMC article.

3

Synthetic lethality of cohesins with PARPs and replication fork mediators.

McLellan JL, O'Neil NJ, Barrett I, Ferree E, van Pel DM, Ushey K, Sipahimalani P, Bryan J, Rose AM, Hieter P. McLellan JL, et al. Among authors: hieter p. PLoS Genet. 2012;8(3):e1002574. doi: 10.1371/journal.pgen.1002574. Epub 2012 Mar 8. PLoS Genet. 2012. PMID: 22412391 Free PMC article.

4

Synthetic lethality and cancer: cohesin and PARP at the replication fork.

O'Neil NJ, van Pel DM, Hieter P. O'Neil NJ, et al. Among authors: hieter p. Trends Genet. 2013 May;29(5):290-7. doi: 10.1016/j.tig.2012.12.004. Epub 2013 Jan 18. Trends Genet. 2013. PMID: 23333522 Free PMC article. Review.

5

Saccharomyces cerevisiae genetics predicts candidate therapeutic genetic interactions at the mammalian replication fork.

van Pel DM, Stirling PC, Minaker SW, Sipahimalani P, Hieter P. van Pel DM, et al. Among authors: hieter p. G3 (Bethesda). 2013 Feb;3(2):273-82. doi: 10.1534/g3.112.004754. Epub 2013 Feb 1. G3 (Bethesda). 2013. PMID: 23390603 Free PMC article.

6

Synthetic lethal targeting of superoxide dismutase 1 selectively kills RAD54B-deficient colorectal cancer cells.

Sajesh BV, Bailey M, Lichtensztejn Z, Hieter P, McManus KJ. Sajesh BV, et al. Among authors: hieter p. Genetics. 2013 Nov;195(3):757-67. doi: 10.1534/genetics.113.156836. Epub 2013 Sep 3. Genetics. 2013. PMID: 24002644 Free PMC article.

7

Proteasome nuclear activity affects chromosome stability by controlling the turnover of Mms22, a protein important for DNA repair.

Ben-Aroya S, Agmon N, Yuen K, Kwok T, McManus K, Kupiec M, Hieter P. Ben-Aroya S, et al. Among authors: hieter p. PLoS Genet. 2010 Feb 19;6(2):e1000852. doi: 10.1371/journal.pgen.1000852. PLoS Genet. 2010. PMID: 20174551 Free PMC article.

8

Glioblastoma cells containing mutations in the cohesin component STAG2 are sensitive to PARP inhibition.

Bailey ML, O'Neil NJ, van Pel DM, Solomon DA, Waldman T, Hieter P. Bailey ML, et al. Among authors: hieter p. Mol Cancer Ther. 2014 Mar;13(3):724-32. doi: 10.1158/1535-7163.MCT-13-0749. Epub 2013 Dec 19. Mol Cancer Ther. 2014. PMID: 24356817 Free PMC article.

9

Genome-wide synthetic lethal screens identify an interaction between the nuclear envelope protein, Apq12p, and the kinetochore in Saccharomyces cerevisiae.

Montpetit B, Thorne K, Barrett I, Andrews K, Jadusingh R, Hieter P, Measday V. Montpetit B, et al. Among authors: hieter p. Genetics. 2005 Oct;171(2):489-501. doi: 10.1534/genetics.105.045799. Epub 2005 Jul 5. Genetics. 2005. PMID: 15998715 Free PMC article.

10

R-loop-mediated genome instability in mRNA cleavage and polyadenylation mutants.

Stirling PC, Chan YA, Minaker SW, Aristizabal MJ, Barrett I, Sipahimalani P, Kobor MS, Hieter P. Stirling PC, et al. Among authors: hieter p. Genes Dev. 2012 Jan 15;26(2):163-75. doi: 10.1101/gad.179721.111. Genes Dev. 2012. PMID: 22279048 Free PMC article.

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