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PNPLA3 I148M (rs738409) genetic variant is associated with hepatocellular carcinoma in obese individuals.
Burza MA, Pirazzi C, Maglio C, Sjöholm K, Mancina RM, Svensson PA, Jacobson P, Adiels M, Baroni MG, Borén J, Ginanni Corradini S, Montalcini T, Sjöström L, Carlsson LM, Romeo S. Burza MA, et al. Among authors: romeo s. Dig Liver Dis. 2012 Dec;44(12):1037-41. doi: 10.1016/j.dld.2012.05.006. Epub 2012 Jun 15. Dig Liver Dis. 2012. PMID: 22704398 Clinical Trial.
Paradoxical lower serum triglyceride levels and higher type 2 diabetes mellitus susceptibility in obese individuals with the PNPLA3 148M variant.
Palmer CN, Maglio C, Pirazzi C, Burza MA, Adiels M, Burch L, Donnelly LA, Colhoun H, Doney AS, Dillon JF, Pearson ER, McCarthy M, Hattersley AT, Frayling T, Morris AD, Peltonen M, Svensson PA, Jacobson P, Borén J, Sjöström L, Carlsson LM, Romeo S. Palmer CN, et al. Among authors: romeo s. PLoS One. 2012;7(6):e39362. doi: 10.1371/journal.pone.0039362. Epub 2012 Jun 18. PLoS One. 2012. PMID: 22724004 Free PMC article.
Patatin-like phospholipase domain-containing 3 (PNPLA3) I148M (rs738409) affects hepatic VLDL secretion in humans and in vitro.
Pirazzi C, Adiels M, Burza MA, Mancina RM, Levin M, Ståhlman M, Taskinen MR, Orho-Melander M, Perman J, Pujia A, Andersson L, Maglio C, Montalcini T, Wiklund O, Borén J, Romeo S. Pirazzi C, et al. Among authors: romeo s. J Hepatol. 2012 Dec;57(6):1276-82. doi: 10.1016/j.jhep.2012.07.030. Epub 2012 Aug 6. J Hepatol. 2012. PMID: 22878467
PNPLA 3 I148M genetic variant associates with insulin resistance and baseline viral load in HCV genotype 2 but not in genotype 3 infection.
Rembeck K, Maglio C, Lagging M, Christensen PB, Färkkilä M, Langeland N, Buhl MR, Pedersen C, Mørch K, Norkrans G, Hellstrand K, Lindh M, Pirazzi C, Burza MA, Romeo S, Westin J; NORDynamIC group. Rembeck K, et al. Among authors: romeo s. BMC Med Genet. 2012 Sep 14;13:82. doi: 10.1186/1471-2350-13-82. BMC Med Genet. 2012. PMID: 22978414 Free PMC article. Clinical Trial.
The IRS1 rs2943641 variant and risk of future cancer among morbidly obese individuals.
Maglio C, Ericson U, Burza MA, Mancina RM, Pirazzi C, Assarsson JA, Sjöholm K, Baroni MG, Svensson PA, Montalcini T, Pujia A, Sjöström L, Wiklund O, Carlsson LM, Borén J, Orho-Melander M, Romeo S. Maglio C, et al. Among authors: romeo s. J Clin Endocrinol Metab. 2013 Apr;98(4):E785-9. doi: 10.1210/jc.2012-2831. Epub 2013 Feb 15. J Clin Endocrinol Metab. 2013. PMID: 23418314
The COBLL1 C allele is associated with lower serum insulin levels and lower insulin resistance in overweight and obese children.
Mancina RM, Burza MA, Maglio C, Pirazzi C, Sentinelli F, Incani M, Montalcini T, Pujia A, Congiu T, Loche S, Pilia S, Wiklund O, Borén J, Romeo S, Baroni MG. Mancina RM, et al. Among authors: romeo s. Diabetes Metab Res Rev. 2013 Jul;29(5):413-6. doi: 10.1002/dmrr.2408. Diabetes Metab Res Rev. 2013. PMID: 23463496 Free PMC article.
514 results