Jones HM - Search Results

1

Model-based approaches to predict drug-drug interactions associated with hepatic uptake transporters: preclinical, clinical and beyond.

Barton HA, Lai Y, Goosen TC, Jones HM, El-Kattan AF, Gosset JR, Lin J, Varma MV. Barton HA, et al. Among authors: jones hm. Expert Opin Drug Metab Toxicol. 2013 Apr;9(4):459-72. doi: 10.1517/17425255.2013.759210. Epub 2013 Jan 21. Expert Opin Drug Metab Toxicol. 2013. PMID: 23331046 Review.

2

In vitro evaluation of hepatic transporter-mediated clinical drug-drug interactions: hepatocyte model optimization and retrospective investigation.

Bi YA, Kimoto E, Sevidal S, Jones HM, Barton HA, Kempshall S, Whalen KM, Zhang H, Ji C, Fenner KS, El-Kattan AF, Lai Y. Bi YA, et al. Among authors: jones hm. Drug Metab Dispos. 2012 Jun;40(6):1085-92. doi: 10.1124/dmd.111.043489. Epub 2012 Mar 1. Drug Metab Dispos. 2012. PMID: 22381335 Review.

3

The evolution of the OATP hepatic uptake transport protein family in DMPK sciences: from obscure liver transporters to key determinants of hepatobiliary clearance.

Fenner KS, Jones HM, Ullah M, Kempshall S, Dickins M, Lai Y, Morgan P, Barton HA. Fenner KS, et al. Among authors: jones hm. Xenobiotica. 2012 Jan;42(1):28-45. doi: 10.3109/00498254.2011.626464. Epub 2011 Nov 11. Xenobiotica. 2012. PMID: 22077101 Review.

4

Mechanistic pharmacokinetic modeling for the prediction of transporter-mediated disposition in humans from sandwich culture human hepatocyte data.

Jones HM, Barton HA, Lai Y, Bi YA, Kimoto E, Kempshall S, Tate SC, El-Kattan A, Houston JB, Galetin A, Fenner KS. Jones HM, et al. Drug Metab Dispos. 2012 May;40(5):1007-17. doi: 10.1124/dmd.111.042994. Epub 2012 Feb 16. Drug Metab Dispos. 2012. PMID: 22344703

5

Application of PBPK modelling in drug discovery and development at Pfizer.

Jones HM, Dickins M, Youdim K, Gosset JR, Attkins NJ, Hay TL, Gurrell IK, Logan YR, Bungay PJ, Jones BC, Gardner IB. Jones HM, et al. Among authors: jones bc. Xenobiotica. 2012 Jan;42(1):94-106. doi: 10.3109/00498254.2011.627477. Epub 2011 Oct 30. Xenobiotica. 2012. PMID: 22035569

6

A Physiologically-Based Pharmacokinetic Model for the Prediction of Monoclonal Antibody Pharmacokinetics From In Vitro Data.

Jones HM, Zhang Z, Jasper P, Luo H, Avery LB, King LE, Neubert H, Barton HA, Betts AM, Webster R. Jones HM, et al. CPT Pharmacometrics Syst Pharmacol. 2019 Oct;8(10):738-747. doi: 10.1002/psp4.12461. Epub 2019 Sep 23. CPT Pharmacometrics Syst Pharmacol. 2019. PMID: 31464379 Free PMC article.

7

Preclinical and clinical pharmacokinetics of PF-02413873, a nonsteroidal progesterone receptor antagonist.

Bungay PJ, Tweedy S, Howe DC, Gibson KR, Jones HM, Mount NM. Bungay PJ, et al. Among authors: jones hm. Drug Metab Dispos. 2011 Aug;39(8):1396-405. doi: 10.1124/dmd.110.037234. Epub 2011 May 4. Drug Metab Dispos. 2011. PMID: 21543556 Clinical Trial.

8

Prediction of human pharmacokinetics from preclinical information: comparative accuracy of quantitative prediction approaches.

Hosea NA, Collard WT, Cole S, Maurer TS, Fang RX, Jones H, Kakar SM, Nakai Y, Smith BJ, Webster R, Beaumont K. Hosea NA, et al. J Clin Pharmacol. 2009 May;49(5):513-33. doi: 10.1177/0091270009333209. Epub 2009 Mar 19. J Clin Pharmacol. 2009. PMID: 19299532

9

Prediction of oral pharmacokinetics of cMet kinase inhibitors in humans: physiologically based pharmacokinetic model versus traditional one-compartment model.

Yamazaki S, Skaptason J, Romero D, Vekich S, Jones HM, Tan W, Wilner KD, Koudriakova T. Yamazaki S, et al. Among authors: jones hm. Drug Metab Dispos. 2011 Mar;39(3):383-93. doi: 10.1124/dmd.110.035857. Epub 2010 Nov 23. Drug Metab Dispos. 2011. PMID: 21098644 Clinical Trial.

10

Application of physiologically based pharmacokinetic modeling to understanding the clinical pharmacokinetics of UK-369,003.

Watson KJ, Davis J, Jones HM. Watson KJ, et al. Among authors: jones hm. Drug Metab Dispos. 2011 Jul;39(7):1203-13. doi: 10.1124/dmd.111.038224. Epub 2011 Mar 30. Drug Metab Dispos. 2011. PMID: 21451120

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