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A HIF-regulated VHL-PTP1B-Src signaling axis identifies a therapeutic target in renal cell carcinoma.
Suwaki N, Vanhecke E, Atkins KM, Graf M, Swabey K, Huang P, Schraml P, Moch H, Cassidy AM, Brewer D, Al-Lazikani B, Workman P, De-Bono J, Kaye SB, Larkin J, Gore ME, Sawyers CL, Nelson P, Beer TM, Geng H, Gao L, Qian DZ, Alumkal JJ, Thomas G, Thomas GV. Suwaki N, et al. Sci Transl Med. 2011 Jun 1;3(85):85ra47. doi: 10.1126/scitranslmed.3002004. Sci Transl Med. 2011. PMID: 21632985 Free PMC article.
Objective assessment of cancer genes for drug discovery.
Patel MN, Halling-Brown MD, Tym JE, Workman P, Al-Lazikani B. Patel MN, et al. Nat Rev Drug Discov. 2013 Jan;12(1):35-50. doi: 10.1038/nrd3913. Nat Rev Drug Discov. 2013. PMID: 23274470 Review.
Drugging cancer genomes.
Workman P, Al-Lazikani B. Workman P, et al. Nat Rev Drug Discov. 2013 Dec;12(12):889-90. doi: 10.1038/nrd4184. Nat Rev Drug Discov. 2013. PMID: 24287764 No abstract available.
Distinctive Behaviors of Druggable Proteins in Cellular Networks.
Mitsopoulos C, Schierz AC, Workman P, Al-Lazikani B. Mitsopoulos C, et al. PLoS Comput Biol. 2015 Dec 23;11(12):e1004597. doi: 10.1371/journal.pcbi.1004597. eCollection 2015 Dec. PLoS Comput Biol. 2015. PMID: 26699810 Free PMC article.
74 results