Beeharry N - Search Results

1

A modified HSP70 inhibitor shows broad activity as an anticancer agent.

Balaburski GM, Leu JI, Beeharry N, Hayik S, Andrake MD, Zhang G, Herlyn M, Villanueva J, Dunbrack RL Jr, Yen T, George DL, Murphy ME. Balaburski GM, et al. Among authors: beeharry n. Mol Cancer Res. 2013 Mar;11(3):219-29. doi: 10.1158/1541-7786.MCR-12-0547-T. Epub 2013 Jan 9. Mol Cancer Res. 2013. PMID: 23303345 Free PMC article.

2

Comparison of the activity of three different HSP70 inhibitors on apoptosis, cell cycle arrest, autophagy inhibition, and HSP90 inhibition.

Budina-Kolomets A, Balaburski GM, Bondar A, Beeharry N, Yen T, Murphy ME. Budina-Kolomets A, et al. Among authors: beeharry n. Cancer Biol Ther. 2014 Feb;15(2):194-9. doi: 10.4161/cbt.26720. Epub 2013 Nov 1. Cancer Biol Ther. 2014. PMID: 24100579 Free PMC article.

3

p53-dependent apoptosis in response to spindle damage is linked to loss of Bub1.

Beeharry N, Yen TJ. Beeharry N, et al. Cancer Biol Ther. 2009 Apr;8(7):645-7. doi: 10.4161/cbt.8.7.8140. Epub 2009 Apr 11. Cancer Biol Ther. 2009. PMID: 19270499 No abstract available.

4

Re-purposing clinical kinase inhibitors to enhance chemosensitivity by overriding checkpoints.

Beeharry N, Banina E, Hittle J, Skobeleva N, Khazak V, Deacon S, Andrake M, Egleston BL, Peterson JR, Astsaturov I, Yen TJ. Beeharry N, et al. Cell Cycle. 2014;13(14):2172-91. doi: 10.4161/cc.29214. Epub 2014 Jun 23. Cell Cycle. 2014. PMID: 24955955 Free PMC article.

5

Centromere fragmentation is a common mitotic defect of S and G2 checkpoint override.

Beeharry N, Rattner JB, Caviston JP, Yen T. Beeharry N, et al. Cell Cycle. 2013 May 15;12(10):1588-97. doi: 10.4161/cc.24740. Epub 2013 Apr 24. Cell Cycle. 2013. PMID: 23624842 Free PMC article.

6

Abnormal cytokinesis after X-irradiation in tumor cells that override the G2 DNA damage checkpoint.

Huang H, Fletcher L, Beeharry N, Daniel R, Kao G, Yen TJ, Muschel RJ. Huang H, et al. Among authors: beeharry n. Cancer Res. 2008 May 15;68(10):3724-32. doi: 10.1158/0008-5472.CAN-08-0479. Cancer Res. 2008. PMID: 18483255 Free article.

7

Oncogenic RAS regulates BRIP1 expression to induce dissociation of BRCA1 from chromatin, inhibit DNA repair, and promote senescence.

Tu Z, Aird KM, Bitler BG, Nicodemus JP, Beeharry N, Xia B, Yen TJ, Zhang R. Tu Z, et al. Among authors: beeharry n. Dev Cell. 2011 Dec 13;21(6):1077-91. doi: 10.1016/j.devcel.2011.10.010. Epub 2011 Dec 1. Dev Cell. 2011. PMID: 22137763 Free PMC article.

8

Dual inhibition of SRC and Aurora kinases induces postmitotic attachment defects and cell death.

Ratushny V, Pathak HB, Beeharry N, Tikhmyanova N, Xiao F, Li T, Litwin S, Connolly DC, Yen TJ, Weiner LM, Godwin AK, Golemis EA. Ratushny V, et al. Among authors: beeharry n. Oncogene. 2012 Mar 8;31(10):1217-27. doi: 10.1038/onc.2011.314. Epub 2011 Jul 25. Oncogene. 2012. PMID: 21785464 Free PMC article.

9

Network modeling of kinase inhibitor polypharmacology reveals pathways targeted in chemical screens.

Ursu O, Gosline SJC, Beeharry N, Fink L, Bhattacharjee V, Huang SC, Zhou Y, Yen T, Fraenkel E. Ursu O, et al. Among authors: beeharry n. PLoS One. 2017 Oct 12;12(10):e0185650. doi: 10.1371/journal.pone.0185650. eCollection 2017. PLoS One. 2017. PMID: 29023490 Free PMC article.

10

HuR posttranscriptionally regulates WEE1: implications for the DNA damage response in pancreatic cancer cells.

Lal S, Burkhart RA, Beeharry N, Bhattacharjee V, Londin ER, Cozzitorto JA, Romeo C, Jimbo M, Norris ZA, Yeo CJ, Sawicki JA, Winter JM, Rigoutsos I, Yen TJ, Brody JR. Lal S, et al. Among authors: beeharry n. Cancer Res. 2014 Feb 15;74(4):1128-40. doi: 10.1158/0008-5472.CAN-13-1915. Cancer Res. 2014. PMID: 24536047 Free PMC article.

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